{"id":224251,"date":"2025-10-30T01:19:29","date_gmt":"2025-10-30T06:19:29","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/10\/detailed-brain-growth-atlas-in-mice-offers-insights-into-brain-development"},"modified":"2025-10-30T01:19:29","modified_gmt":"2025-10-30T06:19:29","slug":"detailed-brain-growth-atlas-in-mice-offers-insights-into-brain-development","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/10\/detailed-brain-growth-atlas-in-mice-offers-insights-into-brain-development","title":{"rendered":"Detailed brain growth atlas in mice offers insights into brain development"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/detailed-brain-growth-atlas-in-mice-offers-insights-into-brain-development.jpg\"><\/a><\/p>\n<p>Brain growth and maturation doesn\u2019t progress in a linear, stepwise fashion. Instead, it\u2019s a dynamic, choreographed sequence that shifts in response to genetics and external stimuli like sight and sound. This is the first high-resolution growth chart to explain changes of key brain cell types in the developing mouse brain, led by a team at Penn State College of Medicine and the Allen Institute for Brain Science.<\/p>\n<p>Using advanced imaging techniques, the researchers constructed a series of 3D atlases that are like time-lapsed maps of the brain during its first two weeks after birth, offering an unparalleled look at a critical period of brain development. It\u2019s a powerful tool to understand healthy brain development and neurodevelopmental disorders, the researchers explained.<\/p>\n<p>The study, <a href=\"https:\/\/www.nature.com\/articles\/s41467-025-64549-x\" target=\"_blank\">published<\/a> in <i>Nature Communications<\/i>, also detailed how regions of the brain change in volume and explained the shift in density of key cell types within them.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Brain growth and maturation doesn\u2019t progress in a linear, stepwise fashion. Instead, it\u2019s a dynamic, choreographed sequence that shifts in response to genetics and external stimuli like sight and sound. This is the first high-resolution growth chart to explain changes of key brain cell types in the developing mouse brain, led by a team at [\u2026]<\/p>\n","protected":false},"author":427,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,412,47],"tags":[],"class_list":["post-224251","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-genetics","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/224251","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/427"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=224251"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/224251\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=224251"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=224251"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=224251"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}