{"id":224169,"date":"2025-10-28T17:07:10","date_gmt":"2025-10-28T22:07:10","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/10\/drug-combo-extends-life-of-frail-male-mice-by-remarkable-73-scientists-find"},"modified":"2025-10-28T17:07:10","modified_gmt":"2025-10-28T22:07:10","slug":"drug-combo-extends-life-of-frail-male-mice-by-remarkable-73-scientists-find","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/10\/drug-combo-extends-life-of-frail-male-mice-by-remarkable-73-scientists-find","title":{"rendered":"Drug combo extends life of frail male mice by \u2018remarkable\u2019 73%, scientists find"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/drug-combo-extends-life-of-frail-male-mice-by-remarkable-73-scientists-find.jpg\"><\/a><\/p>\n<p>\u201cCompared to other established lifespan-extending interventions, Oxytocin+A5i demonstrates unique outcomes, such as significantly (over 70 per cent) increased life expectancy from the start of this therapy in old and frail male mice, and a robust decrease in mortality risk,\u201d they wrote.<\/p>\n<p>The latest study also found that the Oxytocin+A5i treatment reduced chaotic levels of some circulating blood proteins, which are key markers of ageing, bringing their levels back to a more youthful state.<\/p>\n<p>However, after four months of continuous treatment, only male mice showed sustained improvement in these protein levels.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u201cCompared to other established lifespan-extending interventions, Oxytocin+A5i demonstrates unique outcomes, such as significantly (over 70 per cent) increased life expectancy from the start of this therapy in old and frail male mice, and a robust decrease in mortality risk,\u201d they wrote. The latest study also found that the Oxytocin+A5i treatment reduced chaotic levels of some [\u2026]<\/p>\n","protected":false},"author":396,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,269],"tags":[],"class_list":["post-224169","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-life-extension"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/224169","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/396"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=224169"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/224169\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=224169"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=224169"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=224169"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}