{"id":223672,"date":"2025-10-19T23:04:21","date_gmt":"2025-10-20T04:04:21","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/10\/bacteria-boost-chemotherapy-effectiveness"},"modified":"2025-10-19T23:04:21","modified_gmt":"2025-10-20T04:04:21","slug":"bacteria-boost-chemotherapy-effectiveness","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/10\/bacteria-boost-chemotherapy-effectiveness","title":{"rendered":"Bacteria Boost Chemotherapy Effectiveness"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/bacteria-boost-chemotherapy-effectiveness.jpg\"><\/a><\/p>\n<p>The <a href=\"https:\/\/www.cancer.gov\/publications\/dictionaries\/cancer-terms\/def\/microbiome\">microbiome<\/a> encompasses all the microorganisms and viruses that reside in a particular environment in the body. Recent research on the relationship between the gut microbiome and a person\u2019s health has led to an increased understanding of how specific microbiota can benefit or hinder the immune response in cancer patients and an individual\u2019s response to cancer treatment.<\/p>\n<p>A new publication in <em><a href=\"https:\/\/www.cell.com\/cell-systems\/fulltext\/S2405-4712(25)00230-3\">Cell Systems<\/a><\/em> highlights the value of understanding the connections between microbiota and cancer therapy. The study demonstrates that a bacterium associated with colorectal cancer can elicit an anti-cancer effect on tumor cells.<\/p>\n<p>The researchers employed a rigorous four-way screening approach to meticulously examine the molecular-level interactions between the host, microbe, drug, and nutrient. This comprehensive screening approach identified a metabolite, 2-methylisocitrate, that was upregulated in human tumor-associated microbiota, providing a solid foundation for the study\u2019s findings.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The microbiome encompasses all the microorganisms and viruses that reside in a particular environment in the body. Recent research on the relationship between the gut microbiome and a person\u2019s health has led to an increased understanding of how specific microbiota can benefit or hinder the immune response in cancer patients and an individual\u2019s response to [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,1495],"tags":[],"class_list":["post-223672","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-health"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/223672","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=223672"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/223672\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=223672"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=223672"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=223672"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}