{"id":223425,"date":"2025-10-15T03:15:33","date_gmt":"2025-10-15T08:15:33","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/10\/mathematical-model-could-help-boost-drug-efficacy-by-getting-dosing-in-rhythm-with-circadian-clocks"},"modified":"2025-10-15T03:15:33","modified_gmt":"2025-10-15T08:15:33","slug":"mathematical-model-could-help-boost-drug-efficacy-by-getting-dosing-in-rhythm-with-circadian-clocks","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/10\/mathematical-model-could-help-boost-drug-efficacy-by-getting-dosing-in-rhythm-with-circadian-clocks","title":{"rendered":"Mathematical model could help boost drug efficacy by getting dosing in rhythm with circadian clocks"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/mathematical-model-could-help-boost-drug-efficacy-by-getting-dosing-in-rhythm-with-circadian-clocks.jpg\"><\/a><\/p>\n<p>Researchers at the University of Michigan have developed a mathematical model that reveals how our circadian rhythms can have dramatic impacts on how our bodies interact with medicines.<\/p>\n<p>This could help doctors prescribe medicines to have the best intended effect by syncing the dosing up with the natural clocks of their patients.<\/p>\n<p>\u201cThese findings provide a mechanistic basis for chronotherapeutics\u2014optimizing drug efficacy by considering circadian timing,\u201d said the new study\u2019s author Tianyong Yao, an undergraduate researcher in the U-M Department of Mathematics. \u201cThis could improve treatment for conditions such as ADHD, depression and fatigue.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Researchers at the University of Michigan have developed a mathematical model that reveals how our circadian rhythms can have dramatic impacts on how our bodies interact with medicines. This could help doctors prescribe medicines to have the best intended effect by syncing the dosing up with the natural clocks of their patients. \u201cThese findings provide [\u2026]<\/p>\n","protected":false},"author":427,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,2229,47],"tags":[],"class_list":["post-223425","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-mathematics","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/223425","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/427"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=223425"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/223425\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=223425"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=223425"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=223425"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}