{"id":223364,"date":"2025-10-14T03:33:19","date_gmt":"2025-10-14T08:33:19","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/10\/rewriting-the-rules-of-genetics-study-reveals-gene-boundaries-are-dynamic-not-fixed"},"modified":"2025-10-14T03:33:19","modified_gmt":"2025-10-14T08:33:19","slug":"rewriting-the-rules-of-genetics-study-reveals-gene-boundaries-are-dynamic-not-fixed","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/10\/rewriting-the-rules-of-genetics-study-reveals-gene-boundaries-are-dynamic-not-fixed","title":{"rendered":"Rewriting the rules of genetics: Study reveals gene boundaries are dynamic, not fixed"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/rewriting-the-rules-of-genetics-study-reveals-gene-boundaries-are-dynamic-not-fixed3.jpg\"><\/a><\/p>\n<p>Molecular biologists have long believed that the beginning of a gene launched the process of transcription\u2014the process by which a segment of DNA is copied into RNA and then RNA helps make the proteins that cells need to function.<\/p>\n<p>But a new study published in <a href=\"https:\/\/www.science.org\/doi\/10.1126\/science.ado8279\" target=\"_blank\"><i>Science<\/i><\/a> by researchers at Boston University and the University of Massachusetts T.H. Chan School of Medicine challenges that understanding, revealing that the beginning and end of genes are not fixed points, but move together\u2014reshaping how cells build proteins and adapt through evolution.<\/p>\n<p>\u201cThis work rewrites a textbook idea: the beginning of a gene doesn\u2019t just launch transcription\u2014it helps decide where it stops and what protein you ultimately make,\u201d says Ana Fiszbein, assistant professor of biology and faculty fellow of computing &amp; data sciences, and one of the lead authors of the study.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Molecular biologists have long believed that the beginning of a gene launched the process of transcription\u2014the process by which a segment of DNA is copied into RNA and then RNA helps make the proteins that cells need to function. But a new study published in Science by researchers at Boston University and the University of [\u2026]<\/p>\n","protected":false},"author":427,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,1523,412],"tags":[],"class_list":["post-223364","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-computing","category-genetics"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/223364","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/427"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=223364"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/223364\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=223364"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=223364"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=223364"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}