{"id":223076,"date":"2025-10-08T04:29:12","date_gmt":"2025-10-08T09:29:12","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/10\/widely-prescribed-opioid-painkiller-tramadol-not-significantly-effective-for-easing-chronic-pain-analysis-finds"},"modified":"2025-10-08T04:29:12","modified_gmt":"2025-10-08T09:29:12","slug":"widely-prescribed-opioid-painkiller-tramadol-not-significantly-effective-for-easing-chronic-pain-analysis-finds","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/10\/widely-prescribed-opioid-painkiller-tramadol-not-significantly-effective-for-easing-chronic-pain-analysis-finds","title":{"rendered":"Widely-prescribed opioid painkiller tramadol not significantly effective for easing chronic pain, analysis finds"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/widely-prescribed-opioid-painkiller-tramadol-not-significantly-effective-for-easing-chronic-pain-analysis-finds.jpg\"><\/a><\/p>\n<p>The strong opioid painkiller tramadol is not significantly effective at easing the chronic pain for which it\u2019s widely prescribed, finds a pooled data analysis of the available research, <a href=\"https:\/\/ebm.bmj.com\/lookup\/doi\/10.1136\/bmjebm-2025-114101\" target=\"_blank\">published<\/a> in <i>BMJ Evidence-Based Medicine.<\/i><\/p>\n<p>It likely increases the risk of serious side effects, including <a href=\"https:\/\/medicalxpress.com\/tags\/heart+disease\/\" rel=\"tag\" class=\"\">heart disease<\/a>, the findings indicate, prompting the researchers to conclude that the potential harms of tramadol probably outweigh its benefits, and that its use should be minimized.<\/p>\n<p>Tramadol is a dual-action <a href=\"https:\/\/medicalxpress.com\/tags\/opioid\/\" rel=\"tag\" class=\"\">opioid<\/a> widely prescribed for the treatment of moderate to severe acute and chronic pain. As such, it\u2019s recommended in several medical guidelines for pain management, note the researchers.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The strong opioid painkiller tramadol is not significantly effective at easing the chronic pain for which it\u2019s widely prescribed, finds a pooled data analysis of the available research, published in BMJ Evidence-Based Medicine. It likely increases the risk of serious side effects, including heart disease, the findings indicate, prompting the researchers to conclude that the [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-223076","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/223076","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=223076"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/223076\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=223076"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=223076"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=223076"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}