{"id":222997,"date":"2025-10-07T03:26:00","date_gmt":"2025-10-07T08:26:00","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/10\/scientists-reverse-alzheimers-in-mice-using-nanoparticles"},"modified":"2025-10-07T03:26:00","modified_gmt":"2025-10-07T08:26:00","slug":"scientists-reverse-alzheimers-in-mice-using-nanoparticles","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/10\/scientists-reverse-alzheimers-in-mice-using-nanoparticles","title":{"rendered":"Scientists reverse Alzheimer\u2019s in mice using nanoparticles"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/scientists-reverse-alzheimers-in-mice-using-nanoparticles2.jpg\"><\/a><\/p>\n<p>A research team co-led by the Institute for Bioengineering of Catalonia (IBEC) and West China Hospital Sichuan University (WCHSU), working with partners in the UK, has demonstrated a nanotechnology strategy that reverses Alzheimer\u2019s disease in mice.<\/p>\n<p>Unlike traditional nanomedicine, which relies on nanoparticles as carriers for therapeutic molecules, this approach employs nanoparticles that are bioactive in their own right: \u201csupramolecular drugs.\u201d The work has been published in Signal Transduction and Targeted Therapy.<\/p>\n<p>Instead of targeting neurons directly, the therapy restores the proper function of the blood-brain barrier (BBB), the vascular gatekeeper that regulates the brain\u2019s environment. By repairing this critical interface, the researchers achieved a reversal of Alzheimer\u2019s pathology in animal models.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A research team co-led by the Institute for Bioengineering of Catalonia (IBEC) and West China Hospital Sichuan University (WCHSU), working with partners in the UK, has demonstrated a nanotechnology strategy that reverses Alzheimer\u2019s disease in mice. Unlike traditional nanomedicine, which relies on nanoparticles as carriers for therapeutic molecules, this approach employs nanoparticles that are bioactive [\u2026]<\/p>\n","protected":false},"author":427,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1902,11,4,47],"tags":[],"class_list":["post-222997","post","type-post","status-publish","format-standard","hentry","category-bioengineering","category-biotech-medical","category-nanotechnology","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/222997","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/427"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=222997"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/222997\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=222997"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=222997"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=222997"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}