{"id":221515,"date":"2025-09-07T07:18:14","date_gmt":"2025-09-07T12:18:14","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/09\/researchers-uncover-critical-genetic-drivers-of-the-guts-nervous-system-development"},"modified":"2025-09-07T07:18:14","modified_gmt":"2025-09-07T12:18:14","slug":"researchers-uncover-critical-genetic-drivers-of-the-guts-nervous-system-development","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/09\/researchers-uncover-critical-genetic-drivers-of-the-guts-nervous-system-development","title":{"rendered":"Researchers uncover critical genetic drivers of the gut\u2019s \u2018nervous system\u2019 development"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/researchers-uncover-critical-genetic-drivers-of-the-guts-nervous-system-development2.jpg\"><\/a><\/p>\n<p>Vanderbilt researchers, including those from the Vanderbilt Brain Institute, have made significant strides in understanding how the enteric nervous system\u2014sometimes called the \u201cbrain\u201d of the gut\u2014forms and functions.<\/p>\n<p>In a study <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2352345X25001316\" target=\"_blank\">published<\/a> in <i>Cellular and Molecular Gastroenterology and Hepatology<\/i>, the lab of principal investigator, Michelle Southard-Smith, sheds light on how the SOX10 protein contributes to the development of gut cells that play a role in gastrointestinal motility, or how food moves through the digestive system.<\/p>\n<p>The paper is titled \u201cSingle Cell Profiling in the Sox10Dom Hirschsprung Mouse Implicates Hox genes in Enteric Neuron Trajectory Allocation.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Vanderbilt researchers, including those from the Vanderbilt Brain Institute, have made significant strides in understanding how the enteric nervous system\u2014sometimes called the \u201cbrain\u201d of the gut\u2014forms and functions. In a study published in Cellular and Molecular Gastroenterology and Hepatology, the lab of principal investigator, Michelle Southard-Smith, sheds light on how the SOX10 protein contributes to [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,1506,412,47],"tags":[],"class_list":["post-221515","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-food","category-genetics","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/221515","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=221515"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/221515\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=221515"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=221515"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=221515"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}