{"id":221371,"date":"2025-09-03T07:02:47","date_gmt":"2025-09-03T12:02:47","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/09\/puzzle-solving-chemist-helps-boost-synthesis-of-key-bioactive-compounds"},"modified":"2025-09-03T07:02:47","modified_gmt":"2025-09-03T12:02:47","slug":"puzzle-solving-chemist-helps-boost-synthesis-of-key-bioactive-compounds","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/09\/puzzle-solving-chemist-helps-boost-synthesis-of-key-bioactive-compounds","title":{"rendered":"Puzzle-solving chemist helps boost synthesis of key bioactive compounds"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/puzzle-solving-chemist-helps-boost-synthesis-of-key-bioactive-compounds2.jpg\"><\/a><\/p>\n<p>A new approach to an established reaction boosts the ability to synthesize vinylic ethers\u2014key building blocks for many molecules important to human health. The journal <i>Organic Letters<\/i> <a href=\"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.orglett.5c01966\" target=\"_blank\">published<\/a> the breakthrough, made by chemists at Emory University.<\/p>\n<p>\u201cOur method is easy to reproduce and is based on widely available and inexpensive compounds,\u201d says San Pham, an Emory Ph.D. candidate and first author of the paper. \u201cWe can apply this method to make multiple natural products, including novel vinylic ethers.\u201d<\/p>\n<p>Her research improves the reliability, yield and generality of what is known as the Chan-Evans-Lam reaction. These enhancements greatly expand the reaction\u2019s potential for the synthesis of complex, biologically active compounds for drug research.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A new approach to an established reaction boosts the ability to synthesize vinylic ethers\u2014key building blocks for many molecules important to human health. The journal Organic Letters published the breakthrough, made by chemists at Emory University. \u201cOur method is easy to reproduce and is based on widely available and inexpensive compounds,\u201d says San Pham, an [\u2026]<\/p>\n","protected":false},"author":396,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,1495],"tags":[],"class_list":["post-221371","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-health"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/221371","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/396"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=221371"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/221371\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=221371"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=221371"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=221371"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}