{"id":221370,"date":"2025-09-03T04:30:27","date_gmt":"2025-09-03T09:30:27","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/09\/switching-off-one-crucial-protein-appears-to-reverse-brain-aging-in-mice"},"modified":"2025-09-03T04:30:27","modified_gmt":"2025-09-03T09:30:27","slug":"switching-off-one-crucial-protein-appears-to-reverse-brain-aging-in-mice","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/09\/switching-off-one-crucial-protein-appears-to-reverse-brain-aging-in-mice","title":{"rendered":"Switching Off One Crucial Protein Appears to Reverse Brain Aging in Mice"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/switching-off-one-crucial-protein-appears-to-reverse-brain-aging-in-mice.jpg\"><\/a><\/p>\n<p>A protein called ferritin light chain 1 (FTL1) may play a significant role in brain aging, a new study reveals, giving scientists a new target for understanding and potentially preventing <a href=\"https:\/\/www.sciencealert.com\/human-brains-rapidly-aged-in-the-pandemic-and-it-wasnt-just-the-virus\">brain deterioration<\/a> and disease.<\/p>\n<p>FTL1 was brought to light through a careful comparison of <a href=\"https:\/\/en.wikipedia.org\/wiki\/Hippocampus\">the hippocampus<\/a> part of the brain in mice of different ages. The hippocampus is involved in memory and learning, and it is one of the regions that suffers most from age-related decline.<\/p>\n<p>The study team found that FLT1 was the one protein in this region that old mice had more of and young mice had less of.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A protein called ferritin light chain 1 (FTL1) may play a significant role in brain aging, a new study reveals, giving scientists a new target for understanding and potentially preventing brain deterioration and disease. FTL1 was brought to light through a careful comparison of the hippocampus part of the brain in mice of different ages. [\u2026]<\/p>\n","protected":false},"author":513,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,269,47],"tags":[],"class_list":["post-221370","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-life-extension","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/221370","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/513"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=221370"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/221370\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=221370"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=221370"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=221370"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}