{"id":220937,"date":"2025-08-25T16:15:17","date_gmt":"2025-08-25T21:15:17","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/08\/potentiation-of-mitochondrial-function-by-mitodreadd-gs-reverses-pharmacological-and-neurodegenerative-cognitive-impairment-in-mice"},"modified":"2025-08-25T16:15:17","modified_gmt":"2025-08-25T21:15:17","slug":"potentiation-of-mitochondrial-function-by-mitodreadd-gs-reverses-pharmacological-and-neurodegenerative-cognitive-impairment-in-mice","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/08\/potentiation-of-mitochondrial-function-by-mitodreadd-gs-reverses-pharmacological-and-neurodegenerative-cognitive-impairment-in-mice","title":{"rendered":"Potentiation of mitochondrial function by mitoDREADD-Gs reverses pharmacological and neurodegenerative cognitive impairment in mice"},"content":{"rendered":"<p style=\"padding-right: 20px\"><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/potentiation-of-mitochondrial-function-by-mitodreadd-gs-reverses-pharmacological-and-neurodegenerative-cognitive-impairment-in-mice.jpg\"><\/a><\/p>\n<p>Activation of Gs signaling at mitochondria by mitoDREADD-Gs increases mitochondrial metabolism, leading to better memory in mouse models of dementia, directly linking brain mitochondrial deficits to cognitive symptoms of neurodegenerative diseases.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Activation of Gs signaling at mitochondria by mitoDREADD-Gs increases mitochondrial metabolism, leading to better memory in mouse models of dementia, directly linking brain mitochondrial deficits to cognitive symptoms of neurodegenerative diseases.<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,47],"tags":[],"class_list":["post-220937","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/220937","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=220937"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/220937\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=220937"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=220937"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=220937"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}