{"id":220884,"date":"2025-08-24T15:03:57","date_gmt":"2025-08-24T20:03:57","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/08\/prefrontal-cortex-astrocytes-modulate-distinct-neuronal-populations-to-control-anxiety-like-behavior"},"modified":"2025-08-24T15:03:57","modified_gmt":"2025-08-24T20:03:57","slug":"prefrontal-cortex-astrocytes-modulate-distinct-neuronal-populations-to-control-anxiety-like-behavior","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/08\/prefrontal-cortex-astrocytes-modulate-distinct-neuronal-populations-to-control-anxiety-like-behavior","title":{"rendered":"Prefrontal cortex astrocytes modulate distinct neuronal populations to control anxiety-like behavior"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/prefrontal-cortex-astrocytes-modulate-distinct-neuronal-populations-to-control-anxiety-like-behavior2.jpg\"><\/a><\/p>\n<p>Whether and how prefrontal astrocyte Ca2+ signaling modulates different neuronal populations in aiding or inhibiting anxiety-like behavior remains not fully understood. Here authors show that prefrontal astrocytes encode anxiogenic cues and modulate excitatory and inhibitory neurons differently. Silencing prefrontal astrocytes heightens anxiety-like behavior and induces proteomic changes in astrocytes and neurons.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Whether and how prefrontal astrocyte Ca2+ signaling modulates different neuronal populations in aiding or inhibiting anxiety-like behavior remains not fully understood. Here authors show that prefrontal astrocytes encode anxiogenic cues and modulate excitatory and inhibitory neurons differently. Silencing prefrontal astrocytes heightens anxiety-like behavior and induces proteomic changes in astrocytes and neurons.<\/p>\n","protected":false},"author":396,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[47],"tags":[],"class_list":["post-220884","post","type-post","status-publish","format-standard","hentry","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/220884","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/396"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=220884"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/220884\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=220884"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=220884"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=220884"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}