{"id":220788,"date":"2025-08-23T08:24:13","date_gmt":"2025-08-23T13:24:13","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/08\/depression-shown-to-be-both-cause-and-consequence-of-poor-health"},"modified":"2025-08-23T08:24:13","modified_gmt":"2025-08-23T13:24:13","slug":"depression-shown-to-be-both-cause-and-consequence-of-poor-health","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/08\/depression-shown-to-be-both-cause-and-consequence-of-poor-health","title":{"rendered":"Depression shown to be both cause and consequence of poor health"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/depression-shown-to-be-both-cause-and-consequence-of-poor-health2.jpg\"><\/a><\/p>\n<p>A large international study led by researchers at the Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, shows that major depressive disorder (MDD) not only increases risk for a wide range of diseases and social problems, but is also partly driven by factors such as loneliness, obesity, smoking, and chronic pain.<\/p>\n<p>The study, <a href=\"https:\/\/www.nature.com\/articles\/s44220-025-00471-x\" target=\"_blank\">published<\/a> in <i>Nature Mental Health<\/i>, applied <a href=\"https:\/\/medicalxpress.com\/tags\/genetic+methods\/\" rel=\"tag\" class=\"\">genetic methods<\/a> to systematically test which traits are causes, and which are consequences, of depression. The findings highlight the double burden of MDD: it both arises from and contributes to poor health, making prevention and treatment particularly urgent.<\/p>\n<p>\u201cWe show that depression sits at the center of a web of health problems,\u201d says Jo\u00eblle Pasman, research associate at Amsterdam UMC and Karolinska Institutet, who led the study. \u201cIt is not only a debilitating condition in itself but also increases the risk of many diseases, while at the same time being triggered by social, behavioral, and medical factors.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A large international study led by researchers at the Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, shows that major depressive disorder (MDD) not only increases risk for a wide range of diseases and social problems, but is also partly driven by factors such as loneliness, obesity, smoking, and chronic pain. The study, published in [\u2026]<\/p>\n","protected":false},"author":427,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,412,1495,47],"tags":[],"class_list":["post-220788","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-genetics","category-health","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/220788","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/427"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=220788"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/220788\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=220788"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=220788"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=220788"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}