{"id":220535,"date":"2025-08-20T15:15:45","date_gmt":"2025-08-20T20:15:45","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/08\/blocking-brain-damage-may-slow-glioblastoma-growth"},"modified":"2025-08-20T15:15:45","modified_gmt":"2025-08-20T20:15:45","slug":"blocking-brain-damage-may-slow-glioblastoma-growth","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/08\/blocking-brain-damage-may-slow-glioblastoma-growth","title":{"rendered":"Blocking brain damage may slow glioblastoma growth"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/blocking-brain-damage-may-slow-glioblastoma-growth2.jpg\"><\/a><\/p>\n<p>Blocking brain damage triggered by a glioblastoma, an aggressive brain cancer, may slow the growth of the cancer and allow the brain to keep working better for longer, according to a new study led by UCL (University College London) researchers.<\/p>\n<p>The study, <a href=\"https:\/\/www.nature.com\/articles\/s41586-025-09411-2\" target=\"_blank\">published<\/a> in <i>Nature<\/i>, looked at glioblastomas in mice. It found that early-stage tumors damaged parts of nerve cells called axons, and that the brain\u2019s natural response to this injury\u2014breaking down and clearing away these damaged axons\u2014accelerated the tumor\u2019s growth.<\/p>\n<p>Mice in whom this natural response was turned off developed less aggressive tumors, lived for longer and maintained normal brain function that persisted to nearly the end of their lives. In contrast, mice who responded to nerve damage as normal developed more <a href=\"https:\/\/medicalxpress.com\/tags\/aggressive+tumors\/\" rel=\"tag\" class=\"\">aggressive tumors<\/a> and progressive disability, the researchers found.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Blocking brain damage triggered by a glioblastoma, an aggressive brain cancer, may slow the growth of the cancer and allow the brain to keep working better for longer, according to a new study led by UCL (University College London) researchers. The study, published in Nature, looked at glioblastomas in mice. It found that early-stage tumors [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,47],"tags":[],"class_list":["post-220535","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/220535","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=220535"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/220535\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=220535"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=220535"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=220535"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}