{"id":220166,"date":"2025-08-15T04:20:21","date_gmt":"2025-08-15T09:20:21","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/08\/multifocus-microscope-pushes-the-limits-of-fast-live-3d-biological-imaging"},"modified":"2025-08-15T04:20:21","modified_gmt":"2025-08-15T09:20:21","slug":"multifocus-microscope-pushes-the-limits-of-fast-live-3d-biological-imaging","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/08\/multifocus-microscope-pushes-the-limits-of-fast-live-3d-biological-imaging","title":{"rendered":"Multifocus microscope pushes the limits of fast live 3D biological imaging"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/multifocus-microscope-pushes-the-limits-of-fast-live-3d-biological-imaging.jpg\"><\/a><\/p>\n<p>Researchers have developed a high-speed 3D imaging microscope that can capture detailed cell dynamics of an entire small whole organism at once. The ability to image 3D changes in real time over a large field of view could lead to new insights in developmental biology and neuroscience.<\/p>\n<p>\u201cTraditional microscopes are constrained by how quickly they can refocus or scan through different depths, which makes it difficult to capture fast, 3D <a href=\"https:\/\/phys.org\/tags\/biological+processes\/\" rel=\"tag\" class=\"\">biological processes<\/a> without distortion or missing information,\u201d said Eduardo Hirata Miyasaki, who performed the work while in Sara Abrahamsson\u2019s lab at the University of California Santa Cruz (UCSC) and is now at the Chan Zuckerberg Biohub.<\/p>\n<p>\u201cOur new system extends the multifocus microscopy (MFM) technique Abrahamsson developed by using a 25-camera array to push the limits of speed and volumetric imaging. This leap in efficiency opens the door to studying small living systems in motion without disrupting them.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Researchers have developed a high-speed 3D imaging microscope that can capture detailed cell dynamics of an entire small whole organism at once. The ability to image 3D changes in real time over a large field of view could lead to new insights in developmental biology and neuroscience. \u201cTraditional microscopes are constrained by how quickly they [\u2026]<\/p>\n","protected":false},"author":427,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3,47],"tags":[],"class_list":["post-220166","post","type-post","status-publish","format-standard","hentry","category-biological","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/220166","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/427"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=220166"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/220166\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=220166"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=220166"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=220166"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}