{"id":220076,"date":"2025-08-14T03:27:48","date_gmt":"2025-08-14T08:27:48","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/08\/bioelectrosynthesis-platform-enables-switch-like-precision-control-of-cell-signaling"},"modified":"2025-08-14T03:27:48","modified_gmt":"2025-08-14T08:27:48","slug":"bioelectrosynthesis-platform-enables-switch-like-precision-control-of-cell-signaling","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/08\/bioelectrosynthesis-platform-enables-switch-like-precision-control-of-cell-signaling","title":{"rendered":"Bioelectrosynthesis platform enables switch-like, precision control of cell signaling"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/bioelectrosynthesis-platform-enables-switch-like-precision-control-of-cell-signaling.jpg\"><\/a><\/p>\n<p>Cells use various signaling molecules to regulate the nervous, immune, and vascular systems. Among these, nitric oxide (NO) and ammonia (NH\u2083) play important roles, but their chemical instability and gaseous nature make them difficult to generate or control externally.<\/p>\n<p>A KAIST research team has developed a platform that generates specific signaling molecules in situ from a single precursor under an applied electrical signal, enabling switch-like, precise spatiotemporal control of cellular responses. This approach could provide a foundation for future medical technologies such as electroceuticals, electrogenetics, and personalized cell therapies.<\/p>\n<p>The research team led by Professor Jimin Park from the Department of Chemical and Biomolecular Engineering, in collaboration with Professor Jihan Kim\u2019s group, has developed a bioelectrosynthesis platform capable of producing either <a href=\"https:\/\/phys.org\/tags\/nitric+oxide\/\" rel=\"tag\" class=\"\">nitric oxide<\/a> or <a href=\"https:\/\/phys.org\/tags\/ammonia\/\" rel=\"tag\" class=\"\">ammonia<\/a> on demand using only an electrical signal. The platform allows control over the timing, spatial range, and duration of cell responses.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Cells use various signaling molecules to regulate the nervous, immune, and vascular systems. Among these, nitric oxide (NO) and ammonia (NH\u2083) play important roles, but their chemical instability and gaseous nature make them difficult to generate or control externally. A KAIST research team has developed a platform that generates specific signaling molecules in situ from [\u2026]<\/p>\n","protected":false},"author":427,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,19,38,412],"tags":[],"class_list":["post-220076","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-chemistry","category-engineering","category-genetics"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/220076","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/427"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=220076"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/220076\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=220076"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=220076"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=220076"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}