{"id":219893,"date":"2025-08-12T04:29:17","date_gmt":"2025-08-12T09:29:17","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/08\/unexpected-resonances-could-boost-nmrs-potency"},"modified":"2025-08-12T04:29:17","modified_gmt":"2025-08-12T09:29:17","slug":"unexpected-resonances-could-boost-nmrs-potency","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/08\/unexpected-resonances-could-boost-nmrs-potency","title":{"rendered":"Unexpected Resonances Could Boost NMR\u2019s Potency"},"content":{"rendered":"<p style=\"padding-right: 20px\"><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/unexpected-resonances-could-boost-nmrs-potency.jpg\"><\/a><\/p>\n<p>A radio-frequency field can be resonant with nuclear spins in a sample even if its frequency does not match a spectroscopic transition\u2014a result that could enable new forms of NMR spectroscopy.<\/p>\n<p>Physical systems often have characteristic frequencies. When excited at such a frequency, they start to resonate. The Broughton Suspension Bridge incident on April 12, 1831, showed how this can go wrong. A detachment of 74 riflemen marched in step over the bridge, accidentally matching its resonance frequency. Before they had crossed, the bridge collapsed. At the much-smaller scale of nuclear magnetic resonance (NMR) spectroscopy, resonant excitation is less dramatic yet very useful. Typically, NMR relies on secular resonance, which occurs when the energy of the radio-frequency photons used in a measurement matches the energy required for flipping the magnetic moment of a nucleus in a static magnetic field. This secular resonance occurs at the so-called Larmor frequency. Structure determination of chemical compounds, experimental observation of protein dynamics, and magnetic resonance imaging rely on this matching.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A radio-frequency field can be resonant with nuclear spins in a sample even if its frequency does not match a spectroscopic transition\u2014a result that could enable new forms of NMR spectroscopy. Physical systems often have characteristic frequencies. When excited at such a frequency, they start to resonate. The Broughton Suspension Bridge incident on April 12, [\u2026]<\/p>\n","protected":false},"author":427,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[19],"tags":[],"class_list":["post-219893","post","type-post","status-publish","format-standard","hentry","category-chemistry"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/219893","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/427"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=219893"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/219893\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=219893"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=219893"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=219893"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}