{"id":219880,"date":"2025-08-12T04:17:19","date_gmt":"2025-08-12T09:17:19","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/08\/iterative-scramble-for-engineering-synthetic-genome-modules-and-chromosomes"},"modified":"2025-08-12T04:17:19","modified_gmt":"2025-08-12T09:17:19","slug":"iterative-scramble-for-engineering-synthetic-genome-modules-and-chromosomes","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/08\/iterative-scramble-for-engineering-synthetic-genome-modules-and-chromosomes","title":{"rendered":"Iterative SCRaMbLE for engineering synthetic genome modules and chromosomes"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/iterative-scramble-for-engineering-synthetic-genome-modules-and-chromosomes.jpg\"><\/a><\/p>\n<p>SCRaMbLE can optimise traits via gene rearrangement but is limited by screening. Here the authors use FACS and long-read sequencing with iterative SCRaMbLE to map genotype diversity and gene arrangements, identifying solutions for improving genome design.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>SCRaMbLE can optimise traits via gene rearrangement but is limited by screening. Here the authors use FACS and long-read sequencing with iterative SCRaMbLE to map genotype diversity and gene arrangements, identifying solutions for improving genome design.<\/p>\n","protected":false},"author":511,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,38],"tags":[],"class_list":["post-219880","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-engineering"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/219880","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/511"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=219880"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/219880\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=219880"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=219880"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=219880"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}