{"id":219625,"date":"2025-08-08T04:03:15","date_gmt":"2025-08-08T09:03:15","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/08\/dna-nanostructures-can-mimic-molecular-organization-of-living-systems-without-chemical-cross-linking"},"modified":"2025-08-08T04:03:15","modified_gmt":"2025-08-08T09:03:15","slug":"dna-nanostructures-can-mimic-molecular-organization-of-living-systems-without-chemical-cross-linking","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/08\/dna-nanostructures-can-mimic-molecular-organization-of-living-systems-without-chemical-cross-linking","title":{"rendered":"DNA nanostructures can mimic molecular organization of living systems without chemical cross-linking"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/dna-nanostructures-can-mimic-molecular-organization-of-living-systems-without-chemical-cross-linking.jpg\"><\/a><\/p>\n<p>Newly developed DNA nanostructures can form flexible, fluid, and stimuli-responsive condensates without relying on chemical cross-linking, <a href=\"https:\/\/pubs.acs.org\/doi\/10.1021\/jacsau.5c00421\" target=\"_blank\">report researchers<\/a> from the Institute of Science Tokyo and Chuo University, in the journal JACS Au.<\/p>\n<p>Owing to a rigid tetrahedral motif that binds the linkers in a specific direction, the resulting string-like structures form condensates with exceptional fluidity and stability. These findings pave the way for adaptive soft materials with potential applications in drug delivery, artificial organelles, and bioengineering platforms.<\/p>\n<p>Within living cells, certain biomolecules can organize themselves into specialized compartments called biomolecular condensates. These droplet-like structures play crucial roles in cellular functions, such as regulating <a href=\"https:\/\/phys.org\/tags\/gene+expression\/\" rel=\"tag\" class=\"\">gene expression<\/a> and <a href=\"https:\/\/phys.org\/tags\/biochemical+reactions\/\" rel=\"tag\" class=\"\">biochemical reactions<\/a>; they essentially represent nature\u2019s clever way of organizing cellular activity without the need for rigid membranes.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Newly developed DNA nanostructures can form flexible, fluid, and stimuli-responsive condensates without relying on chemical cross-linking, report researchers from the Institute of Science Tokyo and Chuo University, in the journal JACS Au. Owing to a rigid tetrahedral motif that binds the linkers in a specific direction, the resulting string-like structures form condensates with exceptional fluidity [\u2026]<\/p>\n","protected":false},"author":511,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1902,11,19,4],"tags":[],"class_list":["post-219625","post","type-post","status-publish","format-standard","hentry","category-bioengineering","category-biotech-medical","category-chemistry","category-nanotechnology"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/219625","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/511"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=219625"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/219625\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=219625"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=219625"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=219625"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}