{"id":219599,"date":"2025-08-07T16:06:51","date_gmt":"2025-08-07T21:06:51","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/08\/chinese-scientists-unveil-major-breakthrough-in-large-scale-dna-editing"},"modified":"2025-08-07T16:06:51","modified_gmt":"2025-08-07T21:06:51","slug":"chinese-scientists-unveil-major-breakthrough-in-large-scale-dna-editing","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/08\/chinese-scientists-unveil-major-breakthrough-in-large-scale-dna-editing","title":{"rendered":"Chinese Scientists Unveil Major Breakthrough in Large-scale DNA Editing"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/logo.chinese-scientists-unveil-major-breakthrough-in-large-scale-dna-editing2.jpg\"><\/a><\/p>\n<p>Chinese scientists have developed a gene editing technology capable of precisely manipulating large DNA segments ranging from thousands to millions of base pairs in both plant and animal cells, marking a significant advance in the field of life sciences.<\/p>\n<p>The research team from the Institute of Genetics and Developmental Biology at the Chinese Academy of Sciences announced the new technology in a study published online Monday in the journal Cell.<\/p>\n<p>The method, called PCE (Programmable Chromosomal Engineering), combines three innovative techniques to enable programmable editing of large chromosome segments. In lab tests, researchers successfully inserted an 18,800-base-pair DNA fragment, replaced a 5,000-base-pair sequence, inverted a 12-million-base-pair chromosomal region, deleted a 4-million-base-pair segment, and even relocated entire chromosomes.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Chinese scientists have developed a gene editing technology capable of precisely manipulating large DNA segments ranging from thousands to millions of base pairs in both plant and animal cells, marking a significant advance in the field of life sciences. The research team from the Institute of Genetics and Developmental Biology at the Chinese Academy of [\u2026]<\/p>\n","protected":false},"author":661,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1902,11,412],"tags":[],"class_list":["post-219599","post","type-post","status-publish","format-standard","hentry","category-bioengineering","category-biotech-medical","category-genetics"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/219599","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/661"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=219599"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/219599\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=219599"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=219599"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=219599"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}