{"id":219572,"date":"2025-08-07T04:30:28","date_gmt":"2025-08-07T09:30:28","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/08\/low-oxygen-air-slows-parkinsons-progression-and-restores-movement-in-mice"},"modified":"2025-08-07T04:30:28","modified_gmt":"2025-08-07T09:30:28","slug":"low-oxygen-air-slows-parkinsons-progression-and-restores-movement-in-mice","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/08\/low-oxygen-air-slows-parkinsons-progression-and-restores-movement-in-mice","title":{"rendered":"Low-oxygen air slows Parkinson\u2019s progression and restores movement in mice"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/low-oxygen-air-slows-parkinsons-progression-and-restores-movement-in-mice.jpg\"><\/a><\/p>\n<p>Researchers from the Broad Institute and Mass General Brigham have shown that a low-oxygen environment\u2014similar to the thin air found at Mount Everest base camp\u2014can protect the brain and restore movement in mice with Parkinson\u2019s-like disease.<\/p>\n<p>The new research, in <i>Nature Neuroscience<\/i>, suggests that cellular dysfunction in Parkinson\u2019s leads to the accumulation of excess oxygen molecules in the brain, which then fuel neurodegeneration\u2014and that reducing <a href=\"https:\/\/medicalxpress.com\/tags\/oxygen+intake\/\" rel=\"tag\" class=\"\">oxygen intake<\/a> could help prevent or even reverse Parkinson\u2019s symptoms.<\/p>\n<p>\u201cThe fact that we actually saw some reversal of neurological damage is really exciting,\u201d said co-senior author Vamsi Mootha, an institute member at the Broad, professor of systems biology and medicine at Harvard Medical School, and a Howard Hughes Medical Institute investigator in the Department of Molecular Biology at Massachusetts General Hospital (MGH), a founding member of the Mass General Brigham healthcare system.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Researchers from the Broad Institute and Mass General Brigham have shown that a low-oxygen environment\u2014similar to the thin air found at Mount Everest base camp\u2014can protect the brain and restore movement in mice with Parkinson\u2019s-like disease. The new research, in Nature Neuroscience, suggests that cellular dysfunction in Parkinson\u2019s leads to the accumulation of excess oxygen [\u2026]<\/p>\n","protected":false},"author":427,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,47],"tags":[],"class_list":["post-219572","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/219572","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/427"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=219572"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/219572\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=219572"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=219572"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=219572"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}