{"id":219469,"date":"2025-08-05T16:09:47","date_gmt":"2025-08-05T21:09:47","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/08\/experiments-add-to-evidence-of-links-between-amyloid-deposits-in-brain-and-bone-marrow"},"modified":"2025-08-05T16:09:47","modified_gmt":"2025-08-05T21:09:47","slug":"experiments-add-to-evidence-of-links-between-amyloid-deposits-in-brain-and-bone-marrow","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/08\/experiments-add-to-evidence-of-links-between-amyloid-deposits-in-brain-and-bone-marrow","title":{"rendered":"Experiments add to evidence of links between amyloid deposits in brain and bone marrow"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/experiments-add-to-evidence-of-links-between-amyloid-deposits-in-brain-and-bone-marrow.jpg\"><\/a><\/p>\n<p>A recent study led by a team of researchers at The Johns Hopkins University School of Medicine examining aging mice has provided what is believed to be the first evidence that amyloid beta protein\u2014small, sticky protein fragment found in people with Alzheimer\u2019s disease (AD)\u2014particles build up in the bone marrow of the animals, although not in the exact same form as the large, dense plaques found in the brains of people with Alzheimer\u2019s disease.<\/p>\n<p>\u201cAlthough amyloid buildup has been found in organs outside the brain\u2014such as the heart, kidneys, and nerves\u2014it remains unclear whether similar deposits form in bone or <a href=\"https:\/\/medicalxpress.com\/tags\/bone+marrow\/\" rel=\"tag\" class=\"\">bone marrow<\/a> with aging or in Alzheimer\u2019s disease,\u201d says contributing study author Mei Wan, Ph.D., professor of the department of Orthopedic Surgery.<\/p>\n<p>\u201cWhile brain amyloid has been extensively studied for its role in memory loss and neurodegeneration, far less is known about amyloid elsewhere in the body. In fact, almost nothing is known about whether amyloid forms in the skeleton or how it might contribute to age-related <a href=\"https:\/\/medicalxpress.com\/tags\/bone+loss\/\" rel=\"tag\" class=\"\">bone loss<\/a>.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A recent study led by a team of researchers at The Johns Hopkins University School of Medicine examining aging mice has provided what is believed to be the first evidence that amyloid beta protein\u2014small, sticky protein fragment found in people with Alzheimer\u2019s disease (AD)\u2014particles build up in the bone marrow of the animals, although not [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,269,47],"tags":[],"class_list":["post-219469","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-life-extension","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/219469","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=219469"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/219469\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=219469"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=219469"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=219469"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}