{"id":218850,"date":"2025-07-27T12:12:54","date_gmt":"2025-07-27T17:12:54","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/07\/mechanism-of-rad51-filament-formation-by-rad52-and-rad55-rad57-in-homologous-recombination"},"modified":"2025-07-27T12:12:54","modified_gmt":"2025-07-27T17:12:54","slug":"mechanism-of-rad51-filament-formation-by-rad52-and-rad55-rad57-in-homologous-recombination","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/07\/mechanism-of-rad51-filament-formation-by-rad52-and-rad55-rad57-in-homologous-recombination","title":{"rendered":"Mechanism of Rad51 filament formation by Rad52 and Rad55-Rad57 in homologous recombination"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/mechanism-of-rad51-filament-formation-by-rad52-and-rad55-rad57-in-homologous-recombination.jpg\"><\/a><\/p>\n<p>The mediator protein Rad52 promotes Rad51 binding onto RPA-coated DNA to initiate homologous recombination. Here, the authors show that Rad52 sorts Rad51 into monomers and stacks the complex on to the ss-dsDNA junction. The Rad55-Rad57 paralog then promotes extension of the Rad51 filament.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The mediator protein Rad52 promotes Rad51 binding onto RPA-coated DNA to initiate homologous recombination. Here, the authors show that Rad52 sorts Rad51 into monomers and stacks the complex on to the ss-dsDNA junction. The Rad55-Rad57 paralog then promotes extension of the Rad51 filament.<\/p>\n","protected":false},"author":396,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-218850","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/218850","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/396"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=218850"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/218850\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=218850"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=218850"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=218850"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}