{"id":218792,"date":"2025-07-26T12:12:23","date_gmt":"2025-07-26T17:12:23","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/07\/neuropathic-pain-and-distinct-caspr2-autoantibody-igg-subclasses-drive-neuronal-hyperexcitability"},"modified":"2025-07-26T12:12:23","modified_gmt":"2025-07-26T17:12:23","slug":"neuropathic-pain-and-distinct-caspr2-autoantibody-igg-subclasses-drive-neuronal-hyperexcitability","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/07\/neuropathic-pain-and-distinct-caspr2-autoantibody-igg-subclasses-drive-neuronal-hyperexcitability","title":{"rendered":"Neuropathic Pain and Distinct CASPR2 Autoantibody IgG Subclasses Drive Neuronal Hyperexcitability"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/neuropathic-pain-and-distinct-caspr2-autoantibody-igg-subclasses-drive-neuronal-hyperexcitability2.jpg\"><\/a><\/p>\n<p>The authors in this study examined the functional mechanisms of anti-CASPR2 aAbs from patients with and without pain on nociceptive neurons and the role of IgG subclasses.<\/p>\n<hr>\n<p>Background and Objectives.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The authors in this study examined the functional mechanisms of anti-CASPR2 aAbs from patients with and without pain on nociceptive neurons and the role of IgG subclasses. Background and Objectives.<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,47],"tags":[],"class_list":["post-218792","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/218792","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=218792"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/218792\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=218792"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=218792"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=218792"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}