{"id":218590,"date":"2025-07-24T00:08:01","date_gmt":"2025-07-24T05:08:01","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/07\/a-naked-mole-rat-gene-was-put-into-mice-and-it-made-them-live-longer"},"modified":"2025-07-24T00:08:01","modified_gmt":"2025-07-24T05:08:01","slug":"a-naked-mole-rat-gene-was-put-into-mice-and-it-made-them-live-longer","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/07\/a-naked-mole-rat-gene-was-put-into-mice-and-it-made-them-live-longer","title":{"rendered":"A Naked Mole Rat Gene Was Put Into Mice, And It Made Them Live Longer"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/a-naked-mole-rat-gene-was-put-into-mice-and-it-made-them-live-longer.jpg\"><\/a><\/p>\n<p>Naked mole rats are well known for living far longer lives than any rodent <a href=\"https:\/\/elifesciences.org\/articles\/31157\">ought to have<\/a>. It\u2019s just one of their amazing talents for surviving <a href=\"https:\/\/www.sciencealert.com\/mole-rats-evolved-hearing-loss-just-to-cope-with-such-a-quiet-environment\">in a challenging<\/a>, even hostile underground environment.<\/p>\n<p>A fascinating new study led by researchers from the University of Rochester in the US has shown a single gene could play a significant role in their longevity, one that could be transferred into other mammals to give their own life spans a nudge.<\/p>\n<p>The gene \u2013 a version of what\u2019s known as hyaluranon synthase 2 \u2013 produces an abundance of high-molecular-mass hyaluronic acid (HMM-HA), a compound already thought to mediate the <a href=\"https:\/\/www.nature.com\/articles\/nature12234\">risk of cancer<\/a> in naked mole rats (<a href=\"https:\/\/en.wikipedia.org\/wiki\/Naked_mole-rat\"><em>Heterocephalus glaber<\/em><\/a>).<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Naked mole rats are well known for living far longer lives than any rodent ought to have. It\u2019s just one of their amazing talents for surviving in a challenging, even hostile underground environment. A fascinating new study led by researchers from the University of Rochester in the US has shown a single gene could play [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,269],"tags":[],"class_list":["post-218590","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-life-extension"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/218590","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=218590"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/218590\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=218590"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=218590"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=218590"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}