{"id":218537,"date":"2025-07-23T08:07:46","date_gmt":"2025-07-23T13:07:46","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/07\/surprising-finding-could-pave-way-for-universal-cancer-vaccine"},"modified":"2025-07-23T08:07:46","modified_gmt":"2025-07-23T13:07:46","slug":"surprising-finding-could-pave-way-for-universal-cancer-vaccine","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/07\/surprising-finding-could-pave-way-for-universal-cancer-vaccine","title":{"rendered":"Surprising finding could pave way for universal cancer vaccine"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/surprising-finding-could-pave-way-for-universal-cancer-vaccine.jpg\"><\/a><\/p>\n<p>An experimental mRNA vaccine boosted the tumor-fighting effects of immunotherapy in a mouse-model study, bringing researchers one step closer to their goal of developing a universal vaccine to \u201cwake up\u201d the immune system against cancer.<\/p>\n<p><a href=\"https:\/\/www.nature.com\/articles\/s41551-025-01380-1\" target=\"_blank\" rel=\"noreferrer noopener\">Published today in Nature Biomedical Engineering<\/a>, the University of Florida study showed that like a one-two punch, pairing the test vaccine with common anticancer drugs called immune checkpoint inhibitors triggered a strong antitumor response.<\/p>\n<p>A surprising element, researchers said, was that they achieved the promising results not by attacking a specific target protein expressed in the tumor, but by simply revving up the immune system \u2014 spurring it to respond as if fighting a virus. They did this by stimulating the expression of a protein called PD-L1 inside of tumors, making them more receptive to treatment. The research was supported by multiple federal agencies and foundations, including the National Institutes of Health.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>An experimental mRNA vaccine boosted the tumor-fighting effects of immunotherapy in a mouse-model study, bringing researchers one step closer to their goal of developing a universal vaccine to \u201cwake up\u201d the immune system against cancer. Published today in Nature Biomedical Engineering, the University of Florida study showed that like a one-two punch, pairing the test [\u2026]<\/p>\n","protected":false},"author":534,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,1495],"tags":[],"class_list":["post-218537","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-health"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/218537","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/534"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=218537"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/218537\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=218537"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=218537"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=218537"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}