{"id":218364,"date":"2025-07-20T14:06:10","date_gmt":"2025-07-20T19:06:10","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/07\/noncanonical-and-mortality-defining-toxicities-of-car-t-cell-therapy"},"modified":"2025-07-20T14:06:10","modified_gmt":"2025-07-20T19:06:10","slug":"noncanonical-and-mortality-defining-toxicities-of-car-t-cell-therapy","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/07\/noncanonical-and-mortality-defining-toxicities-of-car-t-cell-therapy","title":{"rendered":"Noncanonical and mortality-defining toxicities of CAR T cell therapy"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/noncanonical-and-mortality-defining-toxicities-of-car-t-cell-therapy.jpg\"><\/a><\/p>\n<p>This Review summarizes the current knowledge on mortality-defining toxicities of chimeric antigen receptor T cell therapies beyond cytokine-release syndrome and immune effector cell-associated neurotoxicity syndrome. The authors discuss underlying mechanisms and how these affect timing and management, and outline key unmet needs and future priorities.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>This Review summarizes the current knowledge on mortality-defining toxicities of chimeric antigen receptor T cell therapies beyond cytokine-release syndrome and immune effector cell-associated neurotoxicity syndrome. The authors discuss underlying mechanisms and how these affect timing and management, and outline key unmet needs and future priorities.<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[],"class_list":["post-218364","post","type-post","status-publish","format-standard","hentry","category-futurism"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/218364","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=218364"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/218364\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=218364"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=218364"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=218364"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}