{"id":218213,"date":"2025-07-18T06:30:13","date_gmt":"2025-07-18T11:30:13","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/07\/gene-essential-for-vitamin-d-absorption-could-help-unlock-treatments-for-cancer-and-autoimmune-diseases"},"modified":"2025-07-18T06:30:13","modified_gmt":"2025-07-18T11:30:13","slug":"gene-essential-for-vitamin-d-absorption-could-help-unlock-treatments-for-cancer-and-autoimmune-diseases","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/07\/gene-essential-for-vitamin-d-absorption-could-help-unlock-treatments-for-cancer-and-autoimmune-diseases","title":{"rendered":"Gene essential for vitamin D absorption could help unlock treatments for cancer and autoimmune diseases"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/gene-essential-for-vitamin-d-absorption-could-help-unlock-treatments-for-cancer-and-autoimmune-diseases.jpg\"><\/a><\/p>\n<p>Vitamin D is not only an essential nutrient, but also the precursor of the hormone calcitriol, indispensable for health. It regulates the uptake of phosphate and calcium necessary for bones by the intestines, as well as cell growth and the proper function of muscles, nerve cells, and the immune system.<\/p>\n<p>Now, researchers <a href=\"https:\/\/www.frontiersin.org\/journals\/endocrinology\/articles\/10.3389\/fendo.2025.1585859\/abstract\" target=\"_blank\">have shown<\/a> for the first time in <i>Frontiers in Endocrinology<\/i> that a particular gene called SDR42E1 is crucial for taking up vitamin D from the gut and further metabolizing it\u2014a discovery with many possible applications in precision medicine, including <a href=\"https:\/\/medicalxpress.com\/tags\/cancer+therapy\/\" rel=\"tag\" class=\"\">cancer therapy<\/a>.<\/p>\n<p>\u201cHere we show that blocking or inhibiting SDR42E1 may selectively stop the growth of cancer cells,\u201d said Dr. Georges Nemer, a professor and associate dean for research at the University College of Health and Life Sciences at Hamad Bin Khalifa University in Qatar, and the study\u2019s corresponding author.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Vitamin D is not only an essential nutrient, but also the precursor of the hormone calcitriol, indispensable for health. It regulates the uptake of phosphate and calcium necessary for bones by the intestines, as well as cell growth and the proper function of muscles, nerve cells, and the immune system. Now, researchers have shown for [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,1495],"tags":[],"class_list":["post-218213","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-health"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/218213","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=218213"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/218213\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=218213"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=218213"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=218213"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}