{"id":217682,"date":"2025-07-12T02:12:56","date_gmt":"2025-07-12T07:12:56","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/07\/antibody-mapping-chip-speeds-up-vaccine-research-by-revealing-hidden-binding-sites-quickly"},"modified":"2025-07-12T02:12:56","modified_gmt":"2025-07-12T07:12:56","slug":"antibody-mapping-chip-speeds-up-vaccine-research-by-revealing-hidden-binding-sites-quickly","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/07\/antibody-mapping-chip-speeds-up-vaccine-research-by-revealing-hidden-binding-sites-quickly","title":{"rendered":"Antibody mapping chip speeds up vaccine research by revealing hidden binding sites quickly"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/antibody-mapping-chip-speeds-up-vaccine-research-by-revealing-hidden-binding-sites-quickly2.jpg\"><\/a><\/p>\n<p>A new microchip invented by Scripps Research scientists can reveal how a person\u2019s antibodies interact with viruses\u2014using just a drop of blood. The technology offers researchers faster, clearer insights that could help accelerate vaccine development and antibody discovery.<\/p>\n<p>\u201cThis lets us take a quick snapshot of antibodies as they are evolving after a vaccine or pathogen exposure,\u201d says Andrew Ward, professor in the Department of Integrative Structural and Computational Biology at Scripps Research and senior author of the new paper published in <a href=\"https:\/\/www.nature.com\/articles\/s41551-025-01411-x\" target=\"_blank\"><i>Nature Biomedical Engineering<\/i><\/a> on June 3, 2025. \u201cWe\u2019ve never been able to do that on this timescale or with such tiny amounts of blood before.\u201d<\/p>\n<p>When someone is infected with a virus, or receives a vaccine, their <a href=\"https:\/\/phys.org\/tags\/immune+system\/\" rel=\"tag\" class=\"\">immune system<\/a> creates new antibodies to recognize the foreign invader. Some antibodies work well against the pathogen, while others attach to it only weakly. Figuring out exactly which parts of the virus the best antibodies stick to is key information for scientists trying to optimize vaccines, since they want to design vaccines that elicit strong, reliable immune responses.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A new microchip invented by Scripps Research scientists can reveal how a person\u2019s antibodies interact with viruses\u2014using just a drop of blood. The technology offers researchers faster, clearer insights that could help accelerate vaccine development and antibody discovery. \u201cThis lets us take a quick snapshot of antibodies as they are evolving after a vaccine or [\u2026]<\/p>\n","protected":false},"author":427,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,1523],"tags":[],"class_list":["post-217682","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-computing"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/217682","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/427"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=217682"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/217682\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=217682"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=217682"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=217682"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}