{"id":217629,"date":"2025-07-11T13:02:22","date_gmt":"2025-07-11T18:02:22","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/07\/cancer-drug-candidate-developed-using-supercomputing-ai-blocks-tumor-growth-without-toxic-side-effect"},"modified":"2025-07-11T13:02:22","modified_gmt":"2025-07-11T18:02:22","slug":"cancer-drug-candidate-developed-using-supercomputing-ai-blocks-tumor-growth-without-toxic-side-effect","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/07\/cancer-drug-candidate-developed-using-supercomputing-ai-blocks-tumor-growth-without-toxic-side-effect","title":{"rendered":"Cancer drug candidate developed using supercomputing &amp; AI blocks tumor growth without toxic side effect"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/cancer-drug-candidate-developed-using-supercomputing-ai-blocks-tumor-growth-without-toxic-side-effect.jpg\"><\/a><\/p>\n<p>A new cancer drug candidate developed by Lawrence Livermore National Laboratory (LLNL), BBOT (BridgeBio Oncology Therapeutics) and the Frederick National Laboratory for Cancer Research (FNLCR) has demonstrated the ability to block tumor growth without triggering a common and debilitating side effect. In early clinical trials, the compound, known as BBO-10203, has shown promise in disrupting a key interaction between two cancer-driving proteins \u2014 RAS and PI3K\u03b1 \u2014 without causing hyperglycemia (high blood-sugar levels), which has historically hindered similar treatments. Published in Science<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A new cancer drug candidate developed by Lawrence Livermore National Laboratory (LLNL), BBOT (BridgeBio Oncology Therapeutics) and the Frederick National Laboratory for Cancer Research (FNLCR) has demonstrated the ability to block tumor growth without triggering a common and debilitating side effect. In early clinical trials, the compound, known as BBO-10203, has shown promise in disrupting [\u2026]<\/p>\n","protected":false},"author":534,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,6,44],"tags":[],"class_list":["post-217629","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-robotics-ai","category-supercomputing"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/217629","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/534"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=217629"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/217629\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=217629"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=217629"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=217629"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}