{"id":217454,"date":"2025-07-09T10:10:43","date_gmt":"2025-07-09T15:10:43","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/07\/major-autism-study-uncovers-biologically-distinct-subtypes-paving-the-way-for-precision-diagnosis-and-care"},"modified":"2025-07-09T10:10:43","modified_gmt":"2025-07-09T15:10:43","slug":"major-autism-study-uncovers-biologically-distinct-subtypes-paving-the-way-for-precision-diagnosis-and-care","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/07\/major-autism-study-uncovers-biologically-distinct-subtypes-paving-the-way-for-precision-diagnosis-and-care","title":{"rendered":"Major autism study uncovers biologically distinct subtypes, paving the way for precision diagnosis and care"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/major-autism-study-uncovers-biologically-distinct-subtypes-paving-the-way-for-precision-diagnosis-and-care.jpg\"><\/a><\/p>\n<p>Researchers at Princeton University and the Simons Foundation have identified four clinically and biologically distinct subtypes of autism, marking a transformative step in understanding the condition\u2019s genetic underpinnings and potential for personalized care.<\/p>\n<p>Analyzing data from over 5,000 children in <a href=\"https:\/\/sparkforautism.org\/portal\/page\/about-spark\" target=\"_blank\">SPARK<\/a>, an <a href=\"https:\/\/medicalxpress.com\/tags\/autism\/\" rel=\"tag\" class=\"\">autism<\/a> cohort study, the researchers used a computational model to group individuals based on their combinations of traits.<\/p>\n<p>The team used a \u201cperson-centered\u201d approach that considered a broad range of over 230 traits in each individual, from social interactions to <a href=\"https:\/\/medicalxpress.com\/tags\/repetitive+behaviors\/\" rel=\"tag\" class=\"\">repetitive behaviors<\/a> to developmental milestones, rather than searching for <a href=\"https:\/\/medicalxpress.com\/tags\/genetic+links\/\" rel=\"tag\" class=\"\">genetic links<\/a> to single traits.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Researchers at Princeton University and the Simons Foundation have identified four clinically and biologically distinct subtypes of autism, marking a transformative step in understanding the condition\u2019s genetic underpinnings and potential for personalized care. Analyzing data from over 5,000 children in SPARK, an autism cohort study, the researchers used a computational model to group individuals based [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,1523,412,47],"tags":[],"class_list":["post-217454","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-computing","category-genetics","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/217454","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=217454"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/217454\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=217454"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=217454"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=217454"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}