{"id":217452,"date":"2025-07-09T10:10:04","date_gmt":"2025-07-09T15:10:04","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/07\/genome-editing-enables-mice-to-produce-their-own-weight-loss-drug-for-months"},"modified":"2025-07-09T10:10:04","modified_gmt":"2025-07-09T15:10:04","slug":"genome-editing-enables-mice-to-produce-their-own-weight-loss-drug-for-months","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/07\/genome-editing-enables-mice-to-produce-their-own-weight-loss-drug-for-months","title":{"rendered":"Genome editing enables mice to produce their own weight-loss drug for months"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/genome-editing-enables-mice-to-produce-their-own-weight-loss-drug-for-months2.jpg\"><\/a><\/p>\n<p>Weight-loss drugs have surged in popularity, promising rapid results with regular injections. Now, researchers from Japan report a way for the body to make its own weight-loss drugs, doing away with injections in favor of a one-time treatment.<\/p>\n<p>In the study, \u201cTargeted In Vivo Gene Integration of a Secretion-Enabled GLP-1 receptor agonist Reverses Diet-induced Non-genetic Obesity and Pre-diabetes,\u201d published in <i>Communications Medicine<\/i>, researchers from the University of Osaka reveal a modified genome editing approach to tackle noncommunicable, multifaceted diseases.<\/p>\n<p>The approach introduced a new protein-coding gene, rather than attempting to correct a mutation in an existing gene and could be the key to lifelong effective weight management.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Weight-loss drugs have surged in popularity, promising rapid results with regular injections. Now, researchers from Japan report a way for the body to make its own weight-loss drugs, doing away with injections in favor of a one-time treatment. In the study, \u201cTargeted In Vivo Gene Integration of a Secretion-Enabled GLP-1 receptor agonist Reverses Diet-induced Non-genetic [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,412],"tags":[],"class_list":["post-217452","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-genetics"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/217452","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=217452"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/217452\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=217452"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=217452"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=217452"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}