{"id":217451,"date":"2025-07-09T10:09:49","date_gmt":"2025-07-09T15:09:49","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/07\/universal-stem-cells-reset-immunity-in-a-systemic-sclerosis-patient"},"modified":"2025-07-09T10:09:49","modified_gmt":"2025-07-09T15:09:49","slug":"universal-stem-cells-reset-immunity-in-a-systemic-sclerosis-patient","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/07\/universal-stem-cells-reset-immunity-in-a-systemic-sclerosis-patient","title":{"rendered":"Universal stem cells reset immunity in a systemic sclerosis patient"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/universal-stem-cells-reset-immunity-in-a-systemic-sclerosis-patient.jpg\"><\/a><\/p>\n<p>Research led by Naval Medical University\u2019s Changzheng Hospital in China reports that an off-the-shelf cell therapy built from induced pluripotent stem cells (iPSCs) loosened life-limiting skin and organ scarring in a woman with systemic sclerosis.<\/p>\n<p>Systemic sclerosis progressively suffocates tissue through immune misfires, collapsed micro-vessels, and runaway collagen conditions that resist standard immunosuppressants, biologics, and anti-fibrotic drugs while driving a 40% 10-year mortality.<\/p>\n<p>Cell-based approaches such as hematopoietic-stem-cell transplants and CAR-T therapies have shown promise but carry high toxicity or labor-intensive custom manufacturing, leaving clinicians and patients in search of safer, more accessible tools.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Research led by Naval Medical University\u2019s Changzheng Hospital in China reports that an off-the-shelf cell therapy built from induced pluripotent stem cells (iPSCs) loosened life-limiting skin and organ scarring in a woman with systemic sclerosis. Systemic sclerosis progressively suffocates tissue through immune misfires, collapsed micro-vessels, and runaway collagen conditions that resist standard immunosuppressants, biologics, and [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-217451","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/217451","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=217451"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/217451\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=217451"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=217451"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=217451"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}