{"id":216976,"date":"2025-07-02T02:02:56","date_gmt":"2025-07-02T07:02:56","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/07\/engineers-create-first-immunocompetent-leukemia-device-for-car-t-immunotherapy-screening"},"modified":"2025-07-02T02:02:56","modified_gmt":"2025-07-02T07:02:56","slug":"engineers-create-first-immunocompetent-leukemia-device-for-car-t-immunotherapy-screening","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/07\/engineers-create-first-immunocompetent-leukemia-device-for-car-t-immunotherapy-screening","title":{"rendered":"Engineers create first immunocompetent leukemia device for CAR T immunotherapy screening"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/engineers-create-first-immunocompetent-leukemia-device-for-car-t-immunotherapy-screening.jpg\"><\/a><\/p>\n<p>A team of researchers led by NYU Tandon School of Engineering\u2019s Weiqiang Chen has developed a miniature device that could transform how blood cancer treatments are tested and tailored for patients.<\/p>\n<p>The team\u2019s microscope slide-sized \u201cleukemia-on-a-chip\u201d is the first laboratory device to successfully combine both the physical structure of bone marrow and a functioning human immune system, an advance that could dramatically accelerate new immunotherapy development.<\/p>\n<p>This innovation comes at a particularly timely moment, as the FDA recently announced a plan to phase out <a href=\"https:\/\/medicalxpress.com\/tags\/animal+testing\/\" rel=\"tag\" class=\"\">animal testing<\/a> requirements for <a href=\"https:\/\/medicalxpress.com\/tags\/monoclonal+antibodies\/\" rel=\"tag\" class=\"\">monoclonal antibodies<\/a> and other drugs, releasing a comprehensive roadmap for reducing animal testing in preclinical safety studies.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A team of researchers led by NYU Tandon School of Engineering\u2019s Weiqiang Chen has developed a miniature device that could transform how blood cancer treatments are tested and tailored for patients. The team\u2019s microscope slide-sized \u201cleukemia-on-a-chip\u201d is the first laboratory device to successfully combine both the physical structure of bone marrow and a functioning human [\u2026]<\/p>\n","protected":false},"author":732,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,1522],"tags":[],"class_list":["post-216976","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-innovation"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/216976","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/732"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=216976"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/216976\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=216976"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=216976"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=216976"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}