{"id":216674,"date":"2025-06-26T14:13:20","date_gmt":"2025-06-26T19:13:20","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/06\/alphagenome-ai-for-better-understanding-the-genome"},"modified":"2025-06-26T14:13:20","modified_gmt":"2025-06-26T19:13:20","slug":"alphagenome-ai-for-better-understanding-the-genome","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/06\/alphagenome-ai-for-better-understanding-the-genome","title":{"rendered":"AlphaGenome: AI for better understanding the genome"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/alphagenome-ai-for-better-understanding-the-genome.jpg\"><\/a><\/p>\n<p>Introducing a new, unifying DNA sequence model that advances regulatory variant-effect prediction and promises to shed new light on genome function \u2014 now available via API.<\/p>\n<p>The genome is our cellular instruction manual. It\u2019s the complete set of DNA which guides nearly every part of a living organism, from appearance and function to growth and reproduction. Small variations in a genome\u2019s DNA sequence can alter an organism\u2019s response to its environment or its susceptibility to disease. But deciphering how the genome\u2019s instructions are read at the molecular level \u2014 and what happens when a small DNA variation occurs \u2014 is still one of biology\u2019s greatest mysteries.<\/p>\n<p>Today, we introduce <a href=\"https:\/\/storage.googleapis.com\/deepmind-media\/papers\/alphagenome.pdf\" rel=\"noopener\" target=\"_blank\">AlphaGenome<\/a>, a new artificial intelligence (AI) tool that more comprehensively and accurately predicts how single variants or mutations in human DNA sequences impact a wide range of biological processes regulating genes. This was enabled, among other factors, by technical advances allowing the model to process long DNA sequences and output high-resolution predictions.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Introducing a new, unifying DNA sequence model that advances regulatory variant-effect prediction and promises to shed new light on genome function \u2014 now available via API. The genome is our cellular instruction manual. It\u2019s the complete set of DNA which guides nearly every part of a living organism, from appearance and function to growth and [\u2026]<\/p>\n","protected":false},"author":599,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,412,6],"tags":[],"class_list":["post-216674","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-genetics","category-robotics-ai"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/216674","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/599"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=216674"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/216674\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=216674"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=216674"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=216674"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}