{"id":216600,"date":"2025-06-25T14:05:35","date_gmt":"2025-06-25T19:05:35","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/06\/rare-mutation-shields-brain-from-alzheimers-by-silencing-inflammation"},"modified":"2025-06-25T14:05:35","modified_gmt":"2025-06-25T19:05:35","slug":"rare-mutation-shields-brain-from-alzheimers-by-silencing-inflammation","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/06\/rare-mutation-shields-brain-from-alzheimers-by-silencing-inflammation","title":{"rendered":"Rare Mutation Shields Brain from Alzheimer\u2019s by Silencing Inflammation"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/rare-mutation-shields-brain-from-alzheimers-by-silencing-inflammation.jpg\"><\/a><\/p>\n<p>A rare genetic mutation known as APOE3-R136S, or the \u201cChristchurch mutation,\u201d appears to protect against Alzheimer\u2019s disease by suppressing inflammatory signaling in the brain\u2019s immune cells.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A rare genetic mutation known as APOE3-R136S, or the \u201cChristchurch mutation,\u201d appears to protect against Alzheimer\u2019s disease by suppressing inflammatory signaling in the brain\u2019s immune cells.<\/p>\n","protected":false},"author":396,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,412,47],"tags":[],"class_list":["post-216600","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-genetics","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/216600","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/396"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=216600"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/216600\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=216600"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=216600"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=216600"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}