{"id":216129,"date":"2025-06-17T10:11:56","date_gmt":"2025-06-17T15:11:56","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/06\/multitissue-single-cell-analysis-reveals-differential-cellular-and-molecular-sensitivity-between-fructose-and-high-fat-high-sucrose-diets"},"modified":"2025-06-17T10:11:56","modified_gmt":"2025-06-17T15:11:56","slug":"multitissue-single-cell-analysis-reveals-differential-cellular-and-molecular-sensitivity-between-fructose-and-high-fat-high-sucrose-diets","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/06\/multitissue-single-cell-analysis-reveals-differential-cellular-and-molecular-sensitivity-between-fructose-and-high-fat-high-sucrose-diets","title":{"rendered":"Multitissue single-cell analysis reveals differential cellular and molecular sensitivity between fructose and high-fat high-sucrose diets"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/multitissue-single-cell-analysis-reveals-differential-cellular-and-molecular-sensitivity-between-fructose-and-high-fat-high-sucrose-diets2.jpg\"><\/a><\/p>\n<p>Chen et al. compared scRNA-seq profiles of four tissues in metabolic syndrome (MetS) models induced by fructose or high-fat high-sucrose diets, revealing differential tissue, cellular, and molecular vulnerability between diets. Regulatory genes and pathways were identified, and networks were rewired in MetS. <i>mt-Rnr2<\/i> was validated as a key regulator.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Chen et al. compared scRNA-seq profiles of four tissues in metabolic syndrome (MetS) models induced by fructose or high-fat high-sucrose diets, revealing differential tissue, cellular, and molecular vulnerability between diets. Regulatory genes and pathways were identified, and networks were rewired in MetS. mt-Rnr2 was validated as a key regulator.<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[],"class_list":["post-216129","post","type-post","status-publish","format-standard","hentry","category-futurism"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/216129","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=216129"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/216129\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=216129"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=216129"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=216129"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}