{"id":216071,"date":"2025-06-17T02:07:46","date_gmt":"2025-06-17T07:07:46","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/06\/scientists-discover-molecule-that-blocks-aging-and-dementia-in-mice"},"modified":"2025-06-17T02:07:46","modified_gmt":"2025-06-17T07:07:46","slug":"scientists-discover-molecule-that-blocks-aging-and-dementia-in-mice","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/06\/scientists-discover-molecule-that-blocks-aging-and-dementia-in-mice","title":{"rendered":"Scientists Discover Molecule That Blocks Aging And Dementia in Mice"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/scientists-discover-molecule-that-blocks-aging-and-dementia-in-mice.jpg\"><\/a><\/p>\n<p>Scientists are looking at ways to tackle <a href=\"https:\/\/www.sciencealert.com\/go\/IaO\" class=\"\" rel=\"nofollow\" target=\"_self\">Alzheimer\u2019s<\/a> and dementia from all kinds of angles, and a new study has identified the molecule <a href=\"https:\/\/en.wikipedia.org\/wiki\/SPARCL1\">hevin<\/a> (or SPARCL-1) as a potential way of preventing cognitive decline.<\/p>\n<p>Hevin is a protein naturally produced in the brain by cells called <a href=\"https:\/\/en.wikipedia.org\/wiki\/Astrocyte\">astrocytes<\/a>. These support-worker cells look after the connections or synapses between neurons, and it\u2019s thought that hevin plays a role in this essential work.<\/p>\n<p>In this new study, researchers from the Federal University of Rio de Janeiro (UFRJ) and the University of S\u00e3o Paulo in Brazil boosted hevin production in the brains of both healthy mice and those with an Alzheimer\u2019s-like disease.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Scientists are looking at ways to tackle Alzheimer\u2019s and dementia from all kinds of angles, and a new study has identified the molecule hevin (or SPARCL-1) as a potential way of preventing cognitive decline. Hevin is a protein naturally produced in the brain by cells called astrocytes. These support-worker cells look after the connections or [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,269,47],"tags":[],"class_list":["post-216071","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-life-extension","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/216071","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=216071"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/216071\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=216071"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=216071"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=216071"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}