{"id":215103,"date":"2025-05-30T17:12:31","date_gmt":"2025-05-30T22:12:31","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/05\/olfactory-neurons-use-unexpected-solid-clusters-to-achieve-genetic-precision"},"modified":"2025-05-30T17:12:31","modified_gmt":"2025-05-30T22:12:31","slug":"olfactory-neurons-use-unexpected-solid-clusters-to-achieve-genetic-precision","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/05\/olfactory-neurons-use-unexpected-solid-clusters-to-achieve-genetic-precision","title":{"rendered":"Olfactory neurons use unexpected \u2018solid\u2019 clusters to achieve genetic precision"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/olfactory-neurons-use-unexpected-solid-clusters-to-achieve-genetic-precision2.jpg\"><\/a><\/p>\n<p>A new <a href=\"https:\/\/doi.org\/10.1038\/s41586-025-09043-6\" target=\"_blank\">study<\/a> published in <i>Nature<\/i> reveals how olfactory sensory neurons (OSNs) achieve extraordinary precision in selecting which genes to express.<\/p>\n<p>The mechanism is surprising in that it involves solid-like molecular condensates that last for days, helping to solve a long-standing puzzle in genome organization.<\/p>\n<p>The research, led by Prof. Stavros Lomvardas from Columbia University, addresses one of biology\u2019s most intriguing questions: How do <a href=\"https:\/\/phys.org\/tags\/olfactory+sensory+neurons\/\" rel=\"tag\" class=\"\">olfactory sensory neurons<\/a> in the nose manage to express only one <a href=\"https:\/\/phys.org\/tags\/olfactory+receptor\/\" rel=\"tag\" class=\"\">olfactory receptor<\/a> (OR) gene out of approximately 1,000 available options?<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A new study published in Nature reveals how olfactory sensory neurons (OSNs) achieve extraordinary precision in selecting which genes to express. The mechanism is surprising in that it involves solid-like molecular condensates that last for days, helping to solve a long-standing puzzle in genome organization. The research, led by Prof. Stavros Lomvardas from Columbia University, [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,412,47],"tags":[],"class_list":["post-215103","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-genetics","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/215103","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=215103"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/215103\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=215103"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=215103"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=215103"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}