{"id":213480,"date":"2025-05-07T13:05:08","date_gmt":"2025-05-07T18:05:08","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/05\/klotho-a-protein-that-promotes-healthy-aging-and-improves-longevity"},"modified":"2025-05-07T13:05:08","modified_gmt":"2025-05-07T18:05:08","slug":"klotho-a-protein-that-promotes-healthy-aging-and-improves-longevity","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/05\/klotho-a-protein-that-promotes-healthy-aging-and-improves-longevity","title":{"rendered":"Klotho: A protein that promotes healthy aging and improves longevity"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/klotho-a-protein-that-promotes-healthy-aging-and-improves-longevity.jpg\"><\/a><\/p>\n<p>An international study led by the Institut de Neuroci\u00e8ncies at the UAB (INc-UAB) has shown that increasing levels of the Klotho protein in mice extends lifespan and improves both physical and cognitive health when aging.<\/p>\n<p>As we grow older, it is natural to lose <a href=\"https:\/\/medicalxpress.com\/tags\/muscle\/\" rel=\"tag\" class=\"\">muscle<\/a> and <a href=\"https:\/\/medicalxpress.com\/tags\/bone+mass\/\" rel=\"tag\" class=\"\">bone mass<\/a>, leading to greater frailty and a higher risk of falls and serious injuries. Cognitively, neurons progressively degenerate and lose connections, while diseases such as Alzheimer\u2019s and Parkinson\u2019s become more prevalent. In a society where the population is steadily aging, reducing these effects is one of the main challenges for research.<\/p>\n<p>Now, in an article <a href=\"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1525001625001200\" target=\"_blank\">published<\/a> in <i>Molecular Therapy<\/i>, an international research team led by Professor Miguel Chill\u00f3n, ICREA researcher at the INc-UAB, has shown that increasing levels of the secreted form of the Klotho protein (s-KL) improves aging in mice.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>An international study led by the Institut de Neuroci\u00e8ncies at the UAB (INc-UAB) has shown that increasing levels of the Klotho protein in mice extends lifespan and improves both physical and cognitive health when aging. As we grow older, it is natural to lose muscle and bone mass, leading to greater frailty and a higher [\u2026]<\/p>\n","protected":false},"author":732,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,269,47],"tags":[],"class_list":["post-213480","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-life-extension","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/213480","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/732"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=213480"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/213480\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=213480"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=213480"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=213480"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}