{"id":213343,"date":"2025-05-06T09:06:32","date_gmt":"2025-05-06T14:06:32","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/05\/key-genetic-code-identified-for-displacing-bacterial-antibiotic-resistance"},"modified":"2025-05-06T09:06:32","modified_gmt":"2025-05-06T14:06:32","slug":"key-genetic-code-identified-for-displacing-bacterial-antibiotic-resistance","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/05\/key-genetic-code-identified-for-displacing-bacterial-antibiotic-resistance","title":{"rendered":"Key genetic code identified for \u2018displacing\u2019 bacterial antibiotic resistance"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/key-genetic-code-identified-for-displacing-bacterial-antibiotic-resistance2.jpg\"><\/a><\/p>\n<p>Birmingham scientists have identified an essential genetic code for a method called plasmid curing, which aims to \u201cdisplace\u201d antibiotic-resistance genes from bacteria.<\/p>\n<p>Plasmids, which are small, circular strands of DNA, play a crucial role in allowing <a href=\"https:\/\/phys.org\/tags\/bacteria\/\" rel=\"tag\" class=\"\">bacteria<\/a> to share beneficial genes rapidly in a changing environment, most concerningly when they carry genes conferring resistance to antibiotics.<\/p>\n<p>Professor Chris Thomas from Birmingham\u2019s School of Biosciences has investigated plasmid curing for many years, and engineered useful \u201cmulti-copy\u201d (many copies in each bacterium) plasmids for this purpose, resulting in a patented, efficient way to displace unwanted plasmids that carry resistance.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Birmingham scientists have identified an essential genetic code for a method called plasmid curing, which aims to \u201cdisplace\u201d antibiotic-resistance genes from bacteria. Plasmids, which are small, circular strands of DNA, play a crucial role in allowing bacteria to share beneficial genes rapidly in a changing environment, most concerningly when they carry genes conferring resistance to [\u2026]<\/p>\n","protected":false},"author":732,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1902,11,412],"tags":[],"class_list":["post-213343","post","type-post","status-publish","format-standard","hentry","category-bioengineering","category-biotech-medical","category-genetics"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/213343","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/732"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=213343"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/213343\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=213343"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=213343"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=213343"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}