{"id":212494,"date":"2025-04-26T17:16:01","date_gmt":"2025-04-26T22:16:01","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/04\/psychosis-inducing-lesions-affect-a-common-brain-circuit-in-the-hippocampus-research-reveals"},"modified":"2025-04-26T17:16:01","modified_gmt":"2025-04-26T22:16:01","slug":"psychosis-inducing-lesions-affect-a-common-brain-circuit-in-the-hippocampus-research-reveals","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/04\/psychosis-inducing-lesions-affect-a-common-brain-circuit-in-the-hippocampus-research-reveals","title":{"rendered":"Psychosis-inducing lesions affect a common brain circuit in the hippocampus, research reveals"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/psychosis-inducing-lesions-affect-a-common-brain-circuit-in-the-hippocampus-research-reveals3.jpg\"><\/a><\/p>\n<p>A new study investigated the brain circuits involved in psychosis\u2014a condition characterized by delusions, hallucinations, disorganized thinking and detachment from reality.<\/p>\n<p>Andrew Pines, MD, MA, a resident in the Department of Psychiatry at Brigham and Women\u2019s Hospital and a researcher in the Center for Brain Circuit Therapeutics, is the lead author of the paper published in <i>JAMA Psychiatry<\/i> titled \u201cMapping Lesions That Cause Psychosis to a Human Brain Circuit and Proposed Stimulation Target.\u201d<\/p>\n<p>Psychosis is the classic symptom of schizophrenia, a <a href=\"https:\/\/medicalxpress.com\/tags\/serious+mental+illness\/\" rel=\"tag\" class=\"\">serious mental illness<\/a> that causes marked disability in otherwise young and healthy patients. The researchers analyzed published cases in which focal brain damage caused psychosis, with the idea that if damaging a brain circuit causes a symptom, then mapping that circuit might tell us about how to treat that symptom.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A new study investigated the brain circuits involved in psychosis\u2014a condition characterized by delusions, hallucinations, disorganized thinking and detachment from reality. Andrew Pines, MD, MA, a resident in the Department of Psychiatry at Brigham and Women\u2019s Hospital and a researcher in the Center for Brain Circuit Therapeutics, is the lead author of the paper published [\u2026]<\/p>\n","protected":false},"author":661,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,47],"tags":[],"class_list":["post-212494","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/212494","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/661"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=212494"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/212494\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=212494"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=212494"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=212494"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}