{"id":212419,"date":"2025-04-25T13:17:25","date_gmt":"2025-04-25T18:17:25","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/04\/ai-helps-unravel-a-cause-of-alzheimers-disease-and-identify-a-therapeutic-candidate"},"modified":"2025-04-25T13:17:25","modified_gmt":"2025-04-25T18:17:25","slug":"ai-helps-unravel-a-cause-of-alzheimers-disease-and-identify-a-therapeutic-candidate","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/04\/ai-helps-unravel-a-cause-of-alzheimers-disease-and-identify-a-therapeutic-candidate","title":{"rendered":"AI helps unravel a cause of Alzheimer\u2019s disease and identify a therapeutic candidate"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/ai-helps-unravel-a-cause-of-alzheimers-disease-and-identify-a-therapeutic-candidate.jpg\"><\/a><\/p>\n<p>A new study found that a gene recently recognized as a biomarker for Alzheimer\u2019s disease is actually a cause of it, due to its previously unknown secondary function. Researchers at the University of California San Diego used artificial intelligence to help both unravel this mystery of Alzheimer\u2019s disease and discover a potential treatment that obstructs the gene\u2019s moonlighting role.<\/p>\n<p>The research team published their results on April 23 in the journal <a href=\"https:\/\/doi.org\/10.1016\/j.cell.2025.03.045\" target=\"_blank\">Cell<\/a>.<\/p>\n<p>About one in nine people aged 65 and older has Alzheimer\u2019s disease, the most common cause of dementia. While some particular <a href=\"https:\/\/medicalxpress.com\/tags\/genes\/\" rel=\"tag\" class=\"\">genes<\/a>, when mutated, can lead to Alzheimer\u2019s, that connection only accounts for a small percentage of all Alzheimer\u2019s patients. The vast majority of patients do not have a mutation in a known disease-causing gene; instead, they have \u201cspontaneous\u201d Alzheimer\u2019s, and the causes for that are unclear.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A new study found that a gene recently recognized as a biomarker for Alzheimer\u2019s disease is actually a cause of it, due to its previously unknown secondary function. Researchers at the University of California San Diego used artificial intelligence to help both unravel this mystery of Alzheimer\u2019s disease and discover a potential treatment that obstructs [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,412,6],"tags":[],"class_list":["post-212419","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-genetics","category-robotics-ai"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/212419","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=212419"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/212419\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=212419"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=212419"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=212419"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}