{"id":212381,"date":"2025-04-25T01:15:46","date_gmt":"2025-04-25T06:15:46","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/04\/metabolic-driver-of-parkinsons-disease-offers-new-target-for-treatment"},"modified":"2025-04-25T01:15:46","modified_gmt":"2025-04-25T06:15:46","slug":"metabolic-driver-of-parkinsons-disease-offers-new-target-for-treatment","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/04\/metabolic-driver-of-parkinsons-disease-offers-new-target-for-treatment","title":{"rendered":"Metabolic driver of Parkinson\u2019s disease offers new target for treatment"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/metabolic-driver-of-parkinsons-disease-offers-new-target-for-treatment.jpg\"><\/a><\/p>\n<p>Researchers have identified a key enzyme driving forms of Parkinson\u2019s disease, and have shown how blocking it restores normal function in animal and cell models, offering a promising new drug target for the condition.<\/p>\n<p>The work is <a href=\"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0896627325002478\" target=\"_blank\">published<\/a> in the journal Neuron.<\/p>\n<p>In Parkinson\u2019s, a protein known as alpha-synuclein builds up in clumps called Lewy bodies in nerve cells in the brain. These clumps of protein stop these cells from functioning normally, eventually leading the cells to die.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Researchers have identified a key enzyme driving forms of Parkinson\u2019s disease, and have shown how blocking it restores normal function in animal and cell models, offering a promising new drug target for the condition. The work is published in the journal Neuron. In Parkinson\u2019s, a protein known as alpha-synuclein builds up in clumps called Lewy [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,47],"tags":[],"class_list":["post-212381","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/212381","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=212381"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/212381\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=212381"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=212381"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=212381"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}