{"id":212337,"date":"2025-04-24T13:32:27","date_gmt":"2025-04-24T18:32:27","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/04\/parvalbumin-interneurons-regulate-rehabilitation-induced-functional-recovery-after-stroke-and-identify-a-rehabilitation-drug"},"modified":"2025-04-24T13:32:27","modified_gmt":"2025-04-24T18:32:27","slug":"parvalbumin-interneurons-regulate-rehabilitation-induced-functional-recovery-after-stroke-and-identify-a-rehabilitation-drug","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/04\/parvalbumin-interneurons-regulate-rehabilitation-induced-functional-recovery-after-stroke-and-identify-a-rehabilitation-drug","title":{"rendered":"Parvalbumin interneurons regulate rehabilitation-induced functional recovery after stroke and identify a rehabilitation drug"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/parvalbumin-interneurons-regulate-rehabilitation-induced-functional-recovery-after-stroke-and-identify-a-rehabilitation-drug.jpg\"><\/a><\/p>\n<p>UCLA researchers have made a significant breakthrough in stroke rehabilitation by developing a drug, DDL-920, that replicates the effects of physical therapy in mice. This discovery could pave the way for new treatments that enhance recovery for stroke patients.\ue206<\/p>\n<p>Key Findings:<\/p>\n<p>- Understanding Stroke-Induced Brain Disconnection: The study revealed that strokes can disrupt brain connections far from the initial damage site, particularly affecting parvalbumin neurons. These neurons are crucial for generating gamma oscillations\u2014brain rhythms essential for coordinated movements.\ue206<\/p>\n<p>- Role of Physical Rehabilitation: Physical therapy was found to restore gamma oscillations and repair connections in parvalbumin neurons, leading to improved motor functions in both mice and human subjects.\ue206<\/p>\n<div class=\"more-link-wrapper\"> <a class=\"more-link\" href=\"https:\/\/lifeboat.com\/blog\/2025\/04\/parvalbumin-interneurons-regulate-rehabilitation-induced-functional-recovery-after-stroke-and-identify-a-rehabilitation-drug\">Continue reading \u201cParvalbumin interneurons regulate rehabilitation-induced functional recovery after stroke and identify a rehabilitation drug\u201d | &gt;<\/a><\/div>\n","protected":false},"excerpt":{"rendered":"<p>UCLA researchers have made a significant breakthrough in stroke rehabilitation by developing a drug, DDL-920, that replicates the effects of physical therapy in mice. This discovery could pave the way for new treatments that enhance recovery for stroke patients.\ue206 Key Findings: \u2014 Understanding Stroke-Induced Brain Disconnection: The study revealed that strokes can disrupt brain connections [\u2026]<\/p>\n","protected":false},"author":701,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,47],"tags":[],"class_list":["post-212337","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/212337","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/701"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=212337"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/212337\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=212337"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=212337"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=212337"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}