{"id":212023,"date":"2025-04-21T17:07:58","date_gmt":"2025-04-21T22:07:58","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/04\/tumor-byproduct-blocks-immune-cells-from-fighting-cancer-offering-new-treatment-target"},"modified":"2025-04-21T17:07:58","modified_gmt":"2025-04-21T22:07:58","slug":"tumor-byproduct-blocks-immune-cells-from-fighting-cancer-offering-new-treatment-target","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/04\/tumor-byproduct-blocks-immune-cells-from-fighting-cancer-offering-new-treatment-target","title":{"rendered":"Tumor byproduct blocks immune cells from fighting cancer, offering new treatment target"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/tumor-byproduct-blocks-immune-cells-from-fighting-cancer-offering-new-treatment-target.jpg\"><\/a><\/p>\n<p>A team of researchers from the University of Chicago, in collaboration with researchers from the University of Pittsburgh, has identified a novel oncometabolite that accumulates in tumors and impairs immune cells\u2019 ability to fight cancer.<\/p>\n<p>The <a href=\"https:\/\/www.nature.com\/articles\/s41556-025-01650-9\" target=\"_blank\">study<\/a>, published in <i>Nature Cell Biology<\/i>, highlights how the metabolic environment of tumors influences the function of T cells, which are critical immune cells responsible for eliminating cancer. The finding opens new possibilities for improving cancer immunotherapy by targeting <a href=\"https:\/\/medicalxpress.com\/tags\/tumor+metabolism\/\" rel=\"tag\" class=\"\">tumor metabolism<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A team of researchers from the University of Chicago, in collaboration with researchers from the University of Pittsburgh, has identified a novel oncometabolite that accumulates in tumors and impairs immune cells\u2019 ability to fight cancer. The study, published in Nature Cell Biology, highlights how the metabolic environment of tumors influences the function of T cells, [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-212023","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/212023","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=212023"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/212023\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=212023"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=212023"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=212023"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}