{"id":211846,"date":"2025-04-19T10:03:41","date_gmt":"2025-04-19T15:03:41","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/04\/delineating-inflammatory-from-non-inflammatory-mechanisms-for-therapy-optimization-in-psoriatic-arthritis"},"modified":"2025-04-19T10:03:41","modified_gmt":"2025-04-19T15:03:41","slug":"delineating-inflammatory-from-non-inflammatory-mechanisms-for-therapy-optimization-in-psoriatic-arthritis","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/04\/delineating-inflammatory-from-non-inflammatory-mechanisms-for-therapy-optimization-in-psoriatic-arthritis","title":{"rendered":"Delineating inflammatory from non-inflammatory mechanisms for therapy optimization in psoriatic arthritis"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/delineating-inflammatory-from-non-inflammatory-mechanisms-for-therapy-optimization-in-psoriatic-arthritis.jpg\"><\/a><\/p>\n<p>In this Perspective, the authors propose that patients with psoriatic arthritis and an inadequate response to therapy can be classified into two distinct subgroups, characterized by persistent inflammatory and non-inflammatory phenotypes, and discuss potential mechanisms underlying these phenotypes, as well as considerations for treatment strategies and trial design.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>In this Perspective, the authors propose that patients with psoriatic arthritis and an inadequate response to therapy can be classified into two distinct subgroups, characterized by persistent inflammatory and non-inflammatory phenotypes, and discuss potential mechanisms underlying these phenotypes, as well as considerations for treatment strategies and trial design.<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-211846","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/211846","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=211846"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/211846\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=211846"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=211846"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=211846"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}