{"id":211498,"date":"2025-04-15T17:11:25","date_gmt":"2025-04-15T22:11:25","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/04\/inflammation-may-be-the-link-between-chronic-pain-and-depression"},"modified":"2025-04-15T17:11:25","modified_gmt":"2025-04-15T22:11:25","slug":"inflammation-may-be-the-link-between-chronic-pain-and-depression","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/04\/inflammation-may-be-the-link-between-chronic-pain-and-depression","title":{"rendered":"Inflammation may be the link between chronic pain and depression"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/inflammation-may-be-the-link-between-chronic-pain-and-depression2.webp\"><\/a><\/p>\n<p>Chronic pain\u2014or pain that lasts at least three months\u2014is closely intertwined with depression. Individuals living with pain\u2019s persistent symptoms may be <a href=\"https:\/\/www.cambridge.org\/core\/journals\/psychological-medicine\/article\/abs\/depression-and-pain-primary-data-and-metaanalysis-among-237-952-people-across-47-low-and-middleincome-countries\/0800F40AFC3B0DFDB231EBC6D1AB4EC6\" target=\"_blank\">up to four times more likely<\/a> to experience depression, research shows.<\/p>\n<p>Almost 30% of people worldwide suffer from a chronic pain condition such as <a href=\"https:\/\/medicalxpress.com\/tags\/low+back+pain\/\" rel=\"tag\" class=\"\">low back pain<\/a> and migraines, and one in three of these patients also report co-existing pain conditions.<\/p>\n<p>Now, a new study <a href=\"https:\/\/www.science.org\/doi\/10.1126\/sciadv.adt1083\" target=\"_blank\">published<\/a> in <i>Science Advances<\/i> shows that a person\u2019s risk of depression increases alongside the number of places in the body in which they experience pain. Furthermore, inflammatory markers such as C-reactive protein (a protein produced by the liver in response to inflammation) help explain the association between pain and depression.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Chronic pain\u2014or pain that lasts at least three months\u2014is closely intertwined with depression. Individuals living with pain\u2019s persistent symptoms may be up to four times more likely to experience depression, research shows. Almost 30% of people worldwide suffer from a chronic pain condition such as low back pain and migraines, and one in three of [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,47],"tags":[],"class_list":["post-211498","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-neuroscience"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/211498","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=211498"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/211498\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=211498"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=211498"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=211498"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}