{"id":211403,"date":"2025-04-14T13:25:23","date_gmt":"2025-04-14T18:25:23","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/04\/how-do-we-know-what-the-earths-climate-was-like-millions-of-years-ago"},"modified":"2025-04-14T13:25:23","modified_gmt":"2025-04-14T18:25:23","slug":"how-do-we-know-what-the-earths-climate-was-like-millions-of-years-ago","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/04\/how-do-we-know-what-the-earths-climate-was-like-millions-of-years-ago","title":{"rendered":"How do we know what the Earth\u2019s climate was like millions of years ago?"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/how-do-we-know-what-the-earths-climate-was-like-millions-of-years-ago.jpg\"><\/a><\/p>\n<p>A new multicenter study by researchers at the Icahn School of Medicine at Mount Sinai, in collaboration with the Clinical Proteomic Tumor Analysis Consortium (CPTAC) and colleagues around the world, has discovered that the genes we are born with\u2014known as germline genetic variants\u2014play a powerful, underappreciated role in how cancer develops and behaves.<\/p>\n<p><a href=\"https:\/\/www.cell.com\/cell\/fulltext\/S0092-8674(25)00344-7\" target=\"_blank\">Published<\/a> in the April 14 online issue of <i>Cell<\/i>, the study, \u201cPrecision Proteogenomics Reveals Pan-Cancer Impact of Germline Variants,\u201d is the first to detail how millions of inherited <a href=\"https:\/\/medicalxpress.com\/tags\/genetic+differences\/\" rel=\"tag\" class=\"\">genetic differences<\/a> influence the activity of thousands of proteins within tumors.<\/p>\n<p>Drawing on data from more than 1,000 patients across 10 different cancer types, the research illustrates how a person\u2019s unique genetic makeup can shape the biology of their cancer.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A new multicenter study by researchers at the Icahn School of Medicine at Mount Sinai, in collaboration with the Clinical Proteomic Tumor Analysis Consortium (CPTAC) and colleagues around the world, has discovered that the genes we are born with\u2014known as germline genetic variants\u2014play a powerful, underappreciated role in how cancer develops and behaves. Published in [\u2026]<\/p>\n","protected":false},"author":662,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,412],"tags":[],"class_list":["post-211403","post","type-post","status-publish","format-standard","hentry","category-biotech-medical","category-genetics"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/211403","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/662"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=211403"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/211403\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=211403"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=211403"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=211403"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}