{"id":211313,"date":"2025-04-13T14:08:53","date_gmt":"2025-04-13T19:08:53","guid":{"rendered":"https:\/\/lifeboat.com\/blog\/2025\/04\/cancer-researchers-identify-the-switch-that-allows-intestinal-cells-to-regenerate-after-injury"},"modified":"2025-04-13T14:08:53","modified_gmt":"2025-04-13T19:08:53","slug":"cancer-researchers-identify-the-switch-that-allows-intestinal-cells-to-regenerate-after-injury","status":"publish","type":"post","link":"https:\/\/lifeboat.com\/blog\/2025\/04\/cancer-researchers-identify-the-switch-that-allows-intestinal-cells-to-regenerate-after-injury","title":{"rendered":"Cancer researchers identify the \u2018switch\u2019 that allows intestinal cells to regenerate after injury"},"content":{"rendered":"<p><a class=\"aligncenter blog-photo\" href=\"https:\/\/lifeboat.com\/blog.images\/cancer-researchers-identify-the-switch-that-allows-intestinal-cells-to-regenerate-after-injury2.jpg\"><\/a><\/p>\n<p>Researchers from the University of Colorado Cancer Center have solved a cellular mystery that may lead to better therapies for colorectal and other types of cancer.<\/p>\n<p>Peter Dempsey, Ph.D., professor of pediatrics\u2013 <a href=\"https:\/\/medicalxpress.com\/tags\/developmental+biology\/\" rel=\"tag\" class=\"\">developmental biology<\/a> in the CU School of Medicine, and Justin Brumbaugh, Ph.D., assistant professor of molecular, cellular, and developmental biology at CU Boulder, recently <a href=\"https:\/\/www.nature.com\/articles\/s41556-024-01580-y\" target=\"_blank\">published<\/a> a paper in the journal <i>Nature Cell Biology<\/i> showing the importance of the H3K36 methylation process in regulating plasticity and regeneration in intestinal cells.<\/p>\n<p>\u201cThe intestine has an enormous ability to regenerate itself after injury, and it does this through a model of dedifferentiation,\u201d Dempsey explains. \u201cThe cells dedifferentiate back into a type of regenerative stem cell after injury, and those <a href=\"https:\/\/medicalxpress.com\/tags\/stem+cells\/\" rel=\"tag\" class=\"\">stem cells<\/a> eventually recover the intestine and turn back to normal cells.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Researchers from the University of Colorado Cancer Center have solved a cellular mystery that may lead to better therapies for colorectal and other types of cancer. Peter Dempsey, Ph.D., professor of pediatrics\u2013 developmental biology in the CU School of Medicine, and Justin Brumbaugh, Ph.D., assistant professor of molecular, cellular, and developmental biology at CU Boulder, [\u2026]<\/p>\n","protected":false},"author":707,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-211313","post","type-post","status-publish","format-standard","hentry","category-biotech-medical"],"_links":{"self":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/211313","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/users\/707"}],"replies":[{"embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/comments?post=211313"}],"version-history":[{"count":0,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/posts\/211313\/revisions"}],"wp:attachment":[{"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/media?parent=211313"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/categories?post=211313"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/lifeboat.com\/blog\/wp-json\/wp\/v2\/tags?post=211313"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}